229024-81-1Relevant articles and documents
Syntheses of spacer-linked neodisaccharides derived from L-Daunosamine
Kirschning, Andreas,Chen, Guang-Wu
, p. 4665 - 4668 (1999)
The preparation of novel head-to-head spacer-linked bisdaunosamine homodimers 8, 15 and 18 is described. The synthesis is achieved by double glycosylation of monosilylated 1,4-butanediol 9 using silyl glycoside 5 as glycosyl donor. Alternatively, olefin metathesis of allyl glycosides α-11 and particularly of α-12 constitutes a second route toward 8 and its unsaturated derivative 15 while non symmetrical dimer 18 has been obtained by cross metathesis of allyl glycosides 11 and 12.