229028-61-9Relevant academic research and scientific papers
Efficient method to prepare hydroxyethylamine-based aspartyl protease inhibitors with diverse P1 side chains
Chino, Masao,Wakao, Masahiro,Ellman, Jonathan A
, p. 6305 - 6310 (2007/10/03)
An efficient procedure for the solid-phase synthesis of hydroxyethylamine-based aspartyl protease inhibitors is described. The 1,2-bromo alcohol 4 is the key intermediate and is prepared in four-steps in good overall yield from commercial available amino acids.
