229323-07-3

Basic information

• Product Name: (S)-3-AMINOMETHYL-1-BENZYLPYRROLIDINE
• Synonyms: (3S)-3-Aminomethyl-1-benzylpyrrolidine;REF DUPL: (S)-3-Aminomethyl-1-benzylpyrrolidine;(3S)-1-(Phenylmethyl)-3-pyrrolidinemethanamine;3-PyrrolidineMethanaMine,1-(phenylMethyl)-, (3S)-
• CAS NO: 229323-07-3
• Molecular Formula: C₁₂H₁₈N₂
• Molecular Weight: 190.29
• Product Categories: pharmacetical
• Mol File: 229323-07-3.mol

Chemical Properties

• Boiling Point: 284℃
• Flash Point: 115℃
• Appearance: /
• Density: 1.040
• Vapor Pressure: 0.003mmHg at 25°C
• Refractive Index: 1.563
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (S)-3-AMINOMETHYL-1-BENZYLPYRROLIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-AMINOMETHYL-1-BENZYLPYRROLIDINE(229323-07-3)
• EPA Substance Registry System: (S)-3-AMINOMETHYL-1-BENZYLPYRROLIDINE(229323-07-3)

Safety Data

• Hazardous Substances Data: 229323-07-3(Hazardous Substances Data)

Usage

Uses

Used in Medicinal Chemistry and Drug Development:
(S)-3-AMINOMETHYL-1-BENZYLPYRROLIDINE is used as a key intermediate in the synthesis of new pharmaceuticals, particularly for the development of chiral drugs. Its unique structure and chirality make it a valuable component in the design and synthesis of enantioselective drugs, which can exhibit improved efficacy and reduced side effects compared to their racemic counterparts.
Used in Organic Synthesis:
In the field of organic synthesis, (S)-3-AMINOMETHYL-1-BENZYLPYRROLIDINE serves as a versatile building block for the creation of more complex compounds. Its functional groups, such as the aminomethyl and benzyl groups, can be further modified or used as starting points for the synthesis of a wide range of organic molecules, including natural products, pharmaceuticals, and other bioactive compounds.
Used in Pharmacology and Biochemistry Research:
(S)-3-AMINOMETHYL-1-BENZYLPYRROLIDINE may exhibit potential biological activities, making it a subject of interest for research in pharmacology and biochemistry. Its unique structure and chirality could lead to the discovery of new biological targets and mechanisms of action, ultimately contributing to the development of novel therapeutic agents and a better understanding of biological processes.

InChI:InChI=1/C12H18N2/c13-8-12-6-7-14(10-12)9-11-4-2-1-3-5-11/h1-5,12H,6-10,13H2/t12-/m0/s1

Upstream product

• 157528-56-8 (R)-1-benzylpyrrolidine-3-carbonitrile 

Downstream Products

• 303111-41-3 (R)-(1-benzyl-pyrrolidin-3-ylmethyl)-carbamic acid tert-butyl ester 
• 303111-42-4 ((S)-1-Benzyl-pyrrolidin-3-ylmethyl)-methyl-amine 

Relevant articles and documents

QUINOLONE ANTIBACTERIAL AGENTS

Compounds of formula (I) wherein A is formula (II), formula (III) or formula (IV), and B is formula (V), formula (VI), or formula (VII), can be used in a variety of applications including use as antibacterial agents.

ANTIBACTERIAL AMINOQUINAZOLIDINEDIONE DERIVATIVES

Compounds of formula (I) wherein: A is Formula (II), Formula (III), or Formula (IV) and B is Formula (V), Formula (VI), or Formula (VII), can be used in a variety of applications including use as antibacterial agents.

Enantio- and diastereocontrolled dopamine D1, D2, D3 and D4 receptor binding of N-(3-pyrrolidinylmethyl)benzamides synthesized from aspartic acid

Subreceptor selectivity tuning of N-(3-pyrrolidinyl)benzamides leading to the selective dopamine D3 ligand ent1h and the derivatives 1g and 1e/ent1e which preferably recognize human D2 or D4 receptors, respectively, is described. Binding profiles were con