22955-30-2Relevant academic research and scientific papers
Iridium catalyzed alkylation of 2′-hydroxyacetophenone with alcohols under thermal or microwave conditions
Hunter, Jamie,Rice, Scott,Lowe, Robert,Pask, Christopher M.,Warriner, Stuart,Sridharan, Visuvanathar
, p. 4400 - 4402 (2017)
2′-Hydroxyacetophenone was alkylated with a range of substituted benzyl and heteroaryl alcohols to afford the corresponding C-alkylated products in good yields under microwave irradiation. The C-alkylated products were reacted with bromoacetonitrile to afford 2-amino-3-benzyl 1,4-naphthoquinone derivatives in moderate yields.
