229616-89-1

Upstream product

• 129792-01-4 benzhydryl 6-oxopenicillinate 
• 167028-46-8 benzhydryl 6-(Z)-(1-tert-butoxycarbonylmethylene)penicillanate 
• 247115-05-5 (2S,4R,5R)-6-[1-tert-Butoxycarbonyl-meth-(Z)-ylidene]-3,3-dimethyl-4,7-dioxo-4λ⁴-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester 
• 229616-87-9 (R)-2-{(R)-2-(Benzothiazol-2-yldisulfanyl)-3-[1-tert-butoxycarbonyl-meth-(Z)-ylidene]-4-oxo-azetidin-1-yl}-3-methyl-but-3-enoic acid benzhydryl ester 
• 47547-28-4 6-aminopenicillanic acid diphenylmethyl ester 
• 229616-88-0 (2S,3R,5R)-3-Acetoxymethyl-6-[1-tert-butoxycarbonyl-meth-(Z)-ylidene]-3-methyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester 

Relevant academic research and scientific papers

The synthesis and evaluation of 6-alkylidene-2'β-substituted penam sulfones as β-lactamase inhibitors

Penicillin sulfones, which structurally incorporate both a 6-position alkylidene substituent and a 2'β substituent, have been synthesized and evaluated as inhibitors of class C and class A serine β-lactamases. Incorporation of the 2'β-substituent generall