229617-34-9

Upstream product

• 1290605-61-6 methyl 2-{3,4-bis[(4-methoxybenzyl)oxy]phenyl}acetate 
• 79248-60-5 [3,4-bis-(4-methoxy-benzyloxy)-phenyl]-acetic acid 4-methoxy-benzyl ester 

Downstream Products

• 1290605-39-8 2-{3,4-Bis[(4-methoxybenzyl)oxy]phenyl}-N-(3-thioxo-3H-1,2,4-dithiazol-5-yl) acetoamide 
• 229617-32-7 (2S,3R,5R)-3-{2-[3,4-Bis-(4-methoxy-benzyloxy)-phenyl]-acetoxymethyl}-6-[1-tert-butoxycarbonyl-meth-(Z)-ylidene]-3-methyl-4,4,7-trioxo-4λ⁶-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester 
• 229617-31-6 (2S,3R,5R)-3-{2-[3,4-Bis-(4-methoxy-benzyloxy)-phenyl]-acetoxymethyl}-6-[1-tert-butoxycarbonyl-meth-(Z)-ylidene]-3-methyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester 

Relevant academic research and scientific papers

DITHIAZOLE COMPOUNDS, MATRIX METALLOPROTEASE INHIBITORS AND EXTERNAL PREPARATIONS FOR THE SKIN

A dithiazole compound or a salt thereof expressed by formula (I): wherein R1, is hydrogen atom, alkyl, etc.; R2 is hydrogen atom, hydroxy, alkyl, aryl, arylalkoxy, arylalkyl, etc.; R3 is one group of formulae (II), (III) and (IV): This compound has an excellent inhibiting action on matrix metalloprotease (MMPs) activity, and is useful for pharmaceutical, cosmetic and skin external compositions.

The synthesis and evaluation of 6-alkylidene-2'β-substituted penam sulfones as β-lactamase inhibitors

Penicillin sulfones, which structurally incorporate both a 6-position alkylidene substituent and a 2'β substituent, have been synthesized and evaluated as inhibitors of class C and class A serine β-lactamases. Incorporation of the 2'β-substituent generall