229620-53-5

Basic information

• Product Name: 3-nitro-2-(4-methylphenoxy)pyridine
• Synonyms: 3-nitro-2-(4-methylphenoxy)pyridine
• CAS NO: 229620-53-5
• Molecular Formula: C12H10N2O3
• Molecular Weight: 230.2194
• Mol File: 229620-53-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-nitro-2-(4-methylphenoxy)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-nitro-2-(4-methylphenoxy)pyridine(229620-53-5)
• EPA Substance Registry System: 3-nitro-2-(4-methylphenoxy)pyridine(229620-53-5)

Safety Data

• Hazardous Substances Data: 229620-53-5(Hazardous Substances Data)

Upstream product

• 5470-18-8 2-Chloro-3-nitropyridine 
• 106-44-5 p-cresol 
• 1121-70-6 sodium 4-methylphenoxide 

Downstream Products

• 353257-52-0 2-(p-tolyloxy)pyridin-3-amine 
• 1423008-65-4 C₁₉H₁₅F₂N₃O₂ 

Relevant articles and documents

Synthesis of pyrido[2,3-b][1,4]benzoxazepines via a Friedel-Crafts cyclization

(Formula Presented.) An efficient and practical method has been developed for the synthesis of 6-aryl-substituted pyrido[2,3-b][1,4]benzoxazepines via a Friedel-Crafts reaction of readily accessible 2-phenoxypyridin-3-amines and aromatic acids.

Kinetics of the reaction of 2-chloro-3-nitro- and 2-chloro-5-nitropyridines with aryloxide ions in methanol

The kinetics of the reaction of 2-chloro-3-nitropyridine (ortho-like) and 2-chloro-5-nitropyridine (para-like) with a series of aryloxide ions were studied in methanol at different temperatures. Plots of ΔH* versus ΔS* for both reactions gave good straight lines with isokinetic temperatures of 168 and 195°C. Good linear relationships were obtained from the plots of log k2 against σ° values with relatively large negative ρ values indicating the formation of Meisenheimer σ-complex intermediates. Plots of log k2 against pKa values gave good straight lines indicating that the reactions show an appreciable degree of bond formation in the transition state. An addition-elimination mechanism is suggested. Copyright