22972-53-8

Basic information

• Product Name: (-)-2,4-Bis-<3,4-trans-p-menthadien-(1,8)-yl-(3)>-olivetol
• Synonyms: (-)-2,4-Bis-<3,4-trans-p-menthadien-(1,8)-yl-(3)>-olivetol
• CAS NO: 22972-53-8
• Molecular Weight: 448.689
• Mol File: 22972-53-8.mol

Chemical Properties

• CAS DataBase Reference: (-)-2,4-Bis-<3,4-trans-p-menthadien-(1,8)-yl-(3)>-olivetol(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-2,4-Bis-<3,4-trans-p-menthadien-(1,8)-yl-(3)>-olivetol(22972-53-8)
• EPA Substance Registry System: (-)-2,4-Bis-<3,4-trans-p-menthadien-(1,8)-yl-(3)>-olivetol(22972-53-8)

Safety Data

• Hazardous Substances Data: 22972-53-8(Hazardous Substances Data)

Upstream product

• 22972-51-6 (1S,4R)-p-mentha-2,8-dien-1-ol 
• 500-66-3 Olivetol 
• 1132-21-4 3,5-dimethoxybenzoic acid 
• 877-88-3 3,5-dimethoxybenzyl bromide 
• 22976-40-5 1,3-dimethoxy-5-pentylbenzene 
• 705-76-0 3,5-dimethoxybenzyl alcohol 

Relevant articles and documents

A Novel and Practical Continuous Flow Chemical Synthesis of Cannabidiol (CBD) and its CBDV and CBDB Analogues

Cannabidiol is one of the main non-psychoactive cannabinoids present in Cannabis sativa and, in the last decade, it is gaining great interest among the scientific community for its pharmaceutical, nutraceutical, and cosmetic applications. Herein, we report the first continuous flow chemical synthesis of cannabidiol (CBD) and its analogues cannabidivarin (CBDV) and cannabidibutol (CBDB). This approach permits to synthesize products in very good yields (55–59 %), limiting the formation of psychoactive and illegal cannabinoids such as tetrahydrocannabinol (THC).

BORON TRIFLUORIDE ETHERATE ON ALUMINA - A MODIFIED LEWIS ACID REAGENT. AN IMPROVED SYNTHESIS OF CANNABIDIOL.

Boron trifluoride etherate on alumina catalyses the condensation of resorcinols and monomethyl resorcinols with several monoterpenoid allylic alcohols: in contrast to paralell reactions with boron trifluoride etherate in solution the products obtained do not undergo further cyclisations.