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N-Acetyl Retigabine, also known as N-Acetyl N-Descarboxyethyl Retigabine, is a metabolite of Retigabine (R189050), an experimental anticonvulsant drug. It is a Certified Spiking Solution suitable for use in retigabine testing methods by LC/MS or GC/MS for various applications. N-Acetyl Retigabine is the primary urinary metabolite of retigabine, an antiepileptic drug developed for the treatment of partial seizures. It is also known as ezogabine and is marketed under the trade names Potiga in the US and Trobalt in the EU.

229970-68-7

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229970-68-7 Usage

Uses

Used in Clinical Toxicology:
N-Acetyl Retigabine is used as a reference material for the development and validation of retigabine testing methods by LC/MS or GC/MS, aiding in the assessment of retigabine levels in biological samples for clinical toxicology purposes.
Used in Medication Monitoring:
N-Acetyl Retigabine serves as a benchmark for monitoring retigabine levels in patients undergoing treatment with the antiepileptic drug, ensuring optimal therapeutic outcomes and minimizing potential side effects.
Used in Urine Drug Testing:
N-Acetyl Retigabine is utilized as a reference compound in urine drug testing to detect and quantify retigabine usage, particularly in cases of drug abuse or compliance with prescribed medication regimens.
Used in Pharmaceutical Research:
N-Acetyl Retigabine is employed as a research tool in the development of new anticonvulsant drugs, providing insights into the metabolism and pharmacokinetics of retigabine and its potential applications in epilepsy treatment.
Used in Forensic Analysis:
N-Acetyl Retigabine is used as a forensic marker in cases where the presence of retigabine or its metabolites may be relevant, such as in post-mortem toxicology or criminal investigations involving the use of antiepileptic drugs.
Used in Anticancer Applications:
Although not explicitly mentioned in the provided materials, N-Acetyl Retigabine could potentially be investigated for its role in cancer research, given its relationship with Retigabine, which has shown anxiolytic properties and may have implications for cancer patients experiencing anxiety related to their condition.
Used in Drug Delivery Systems:
N-Acetyl Retigabine could be explored for its potential use in novel drug delivery systems, similar to gallotannin, to enhance the delivery, bioavailability, and therapeutic outcomes of retigabine in the treatment of epilepsy and other related conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 229970-68-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,9,9,7 and 0 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 229970-68:
(8*2)+(7*2)+(6*9)+(5*9)+(4*7)+(3*0)+(2*6)+(1*8)=177
177 % 10 = 7
So 229970-68-7 is a valid CAS Registry Number.

229970-68-7Upstream product

229970-68-7Downstream Products

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