23002-78-0

Usage

Uses

Used in Pharmaceutical Industry:
1-(2-METHYL-1,3-THIAZOL-4-YL)ETHANONE is utilized as a key intermediate in the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its reactivity allows for the creation of a wide range of chemical structures, which is essential for medicinal chemistry.
Used in Organic Synthesis:
In the field of organic synthesis, 1-(2-METHYL-1,3-THIAZOL-4-YL)ETHANONE is employed as a versatile building block for the creation of complex organic molecules. Its unique chemical properties enable it to participate in numerous reactions, facilitating the synthesis of a broad spectrum of organic compounds.

InChI:InChI=1/C6H7NOS/c1-4(8)6-3-9-5(2)7-6/h3H,1-2H3

Upstream product

• 186581-53-3 diazomethane 
• 20949-84-2 2-methylthiazole-4-carbaldehyde 

Downstream Products

• 107263-89-8 (2-Methyl-4-thiazolyl)acetylene 

Relevant academic research and scientific papers

An efficient protocol for the oxidative hydrolysis of ketone SAMP hydrazones employing SeO2 and H2O2 under buffered (pH 7) conditions

An effective oxidative protocol for the liberation of ketones from SAMP hydrazones employing peroxyselenous acid under aqueous buffered conditions (pH 7) has been developed. The procedure proceeds without epimerization of adjacent stereocenters or dehydration, in representative SAMP alkylation and aldol reaction adducts, respectively.

Selenium Heterocycles. XXXVII. Synthesis of 4-(Thiazol-4-yl)-1,2,3-selenadiazoles and 4-(Selenazol-4-yl)-1,2,3-selenadiazoles

Starting from readily available 2-substituted-4-formylthiazoles and selenazoles, a series of 4-(2-aryl-4-selenazolyl)-1,2,3-selenadiazoles I and 4-(2-substituted-4-thiazolyl)-1,2,3-selenadiazoles II were prepared.Pyrolysis of compound II afforded (2-substituted-4-thiazolyl) acetylenes VII.Addition of potassium hydroxide pellets to an alcoholic solution of II gave 2-substituted-1,4-diselenafulvenes VIII.Decomposition of compound II with base followed by the addition of carbon disulfide gave 5-substituted 2-thioxo-1,3-thiaselenoles XI.