23003-30-7

Basic information

• Product Name: 3-Hydroxy-2-iodo-6-methylpyridine
• Synonyms: 2-Iodo-6-methyl-3-pyridinol, 6-Iodo-2-picolin-5-ol;6-Iodo-2-picolin-5-ol,97%;6-Iodo-2-picolin-5-ol2-Iodo-6-methyl-3-pyridinol;2-Iodo-6-methylpyridin-3-pyridinol ,98%;3-Hydroxy-2-iodo-6-methylpyridine 97%;3-HYDROXY-2-IODO-6-METHYLPYRIDINE;6-IODO-2-PICOLIN-5-OL;2-IODO-6-METHYL-3-HYDROXYPYRIDINE
• CAS NO: 23003-30-7
• Molecular Formula: C₆H₆INO
• Molecular Weight: 235.02
• EINECS: 245-376-9
• Product Categories: Heterocycle-Pyridine series;Pyridines, Pyrimidines, Purines and Pteredines;Pyridine
• Mol File: 23003-30-7.mol
• Article Data: 7

Chemical Properties

• Melting Point: 197-199 °C(lit.)
• Boiling Point: 292 °C at 760 mmHg
• Flash Point: 130.4 °C
• Appearance: Light yellow to yellow powder
• Density: 1.8615 (estimate)
• Vapor Pressure: 0.00108mmHg at 25°C
• Refractive Index: 1.657
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 5.46±0.10(Predicted)
• CAS DataBase Reference: 3-Hydroxy-2-iodo-6-methylpyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Hydroxy-2-iodo-6-methylpyridine(23003-30-7)
• EPA Substance Registry System: 3-Hydroxy-2-iodo-6-methylpyridine(23003-30-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39-24/25
• WGK Germany: 3
• Hazardous Substances Data: 23003-30-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H6INO/c1-4-2-3-5(9)6(7)8-4/h2-3,9H,1H3

Upstream product

• 1121-78-4 5-Hydroxy-2-methylpyridine 

Downstream Products

• 306753-71-9 3-(benzyloxy)-2-iodo-6-methylpyridine 
• 1008562-98-8 (S)-3-[2-(4-chloro-2-fluoro-phenoxy)-6-methyl-pyridin-3-yloxymethyl]-piperidine-1-carboxylic acid tert-butyl ester 
• 1008562-78-4 (S)-3-[2-(4-fluoro-2-methyl-phenoxy)-6-methyl-pyridin-3-yloxymethyl]-piperidine-1-carboxylic acid tert-butyl ester 
• 1008562-86-4 (S)-3-(6-methyl-2-phenoxy-pyridin-3-yloxymethyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 1334784-92-7 2-(2,3-dihydro-[1,4]dioxino[2,3-b]pyridin-6-yl)acetic acid 
• 615568-24-6 2,3-dihydro-[1,4]-dioxino[2,3-b]pyridine-6-carbaldehyde 
• 615568-23-5 (2,3-dihydro-[1,4]dioxino[2,3-b]pyridin-6-yl)methanol 

Relevant articles and documents

Compounds for treating spinal muscular atrophy

Provided herein are compounds, compositions thereof and uses therewith for treating spinal muscular atrophy. In a specific embodiment, provided herein are compounds of a form that may be used to modulate the inclusion of exon 7 of SMN2 into mRNA that is transcribed from the SMN2 gene. In another specific embodiment, provided herein are compounds of a form that may be used to modulate the inclusion of exon 7 of SMN1 into mRNA that is transcribed from the SMN1 gene. In yet another embodiment, provided herein are compounds of a form that may be used to modulate the inclusion of exon 7 of SMN1 and SMN2 into mRNA that is transcribed from the SMN1 and SMN2 genes, respectively.

2,3-DIHYDRO-1H-INDEN-1-YL-2,7-DIAZASPIRO[3.5] NONANE DERIVATIVES

The present invention provides a compound of Formula (I) or a pharmaceutically salt thereof wherein R1, R2, Ra, L, Z, Z1 and Z2 are as defined herein, that act as Ghrelin antagonists or inverse agonists; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by the antagonism of the Ghrelin receptor.

ANTIPRURITICS

It is intended to provide antipruritics (drugs to control itching, antiitch agents and drugs to stop itching). It is found out that a compound having an agonistic activity to the cannabinoid receptor shows an antipruritics effect.