2302-95-6

Basic information

• Product Name: (1E)-3-amino-1-ethylidene-thiourea
• Synonyms: (1E)-3-amino-1-ethylidene-thiourea;Acetaldehyde thiosemicarbazone;Ethanone thiosemicarbazone
• CAS NO: 2302-95-6
• Molecular Formula: C₃H₇N₃S
• Molecular Weight: 0
• Mol File: 2302-95-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 205°Cat760mmHg
• Flash Point: 77.8°C
• Appearance: /
• Density: 1.24g/cm³
• Vapor Pressure: 0.256mmHg at 25°C
• Refractive Index: 1.583
• CAS DataBase Reference: (1E)-3-amino-1-ethylidene-thiourea(CAS DataBase Reference)
• NIST Chemistry Reference: (1E)-3-amino-1-ethylidene-thiourea(2302-95-6)
• EPA Substance Registry System: (1E)-3-amino-1-ethylidene-thiourea(2302-95-6)

Safety Data

• Hazardous Substances Data: 2302-95-6(Hazardous Substances Data)

Usage

General Description

(1E)-3-amino-1-ethylidene-thiourea, also known as aminoguanidine, is a chemical compound with the molecular formula C3H8N4S and a molar mass of 136.19 g/mol. It is a derivative of guanidine and is commonly used as a pharmaceutical intermediate and in the synthesis of various organic compounds. Aminoguanidine is known for its ability to react with aldehydes and ketones to form hydrazones, as well as its potential use as an inhibitor of advanced glycation end products, which are associated with diabetes and other age-related diseases. It has also been studied for its potential antioxidative and anti-inflammatory properties, making it a compound of interest in various fields of research and development.

InChI:InChI=1/C3H7N3S/c1-2-5-3(7)6-4/h2H,4H2,1H3,(H,6,7)/b5-2+

Upstream product

• 75-07-0 acetaldehyde 
• 79-19-6 thiosemicarbazide 

Downstream Products

• 108-33-8 5-methyl-1,3,4-thiadiazol-2-amine 
• 1093187-53-1 [Cu2(μ-Br)2(η1-S-acetaldehyde thiosemicarbazone)2(Ph3P)2] 
• 144-82-1 sulfamethizole 

Relevant articles and documents

Synthesis of Emodin Amide Derivatives Containing 1,3,4-Thiadiazole and Their Inhibitory Activity on Vibrio harveyi

A series of new 1,3,4-thiadiazole Emodin amide derivatives were synthesized through the connection of 5-substituted-1,3,4-thiadiazole-2-amine and Emodin carboxylic acids which were obtained by a two-step procedure starting from Emodin. Vibrio harveyi inhibition activities of the newly prepared compounds were evaluated. Results revealed that all compounds showed different degrees of inhibition on V. harveyi. Among them, compound 7a showed the best V. harveyi inhibition effect and the minimum inhibitory concentration (MIC) was 0.0625 mg/mL.

Monoazo thiazolotriazole disperse dye and preparation method thereof

The invention relates to a monoazo thiazolotriazole disperse dye compound which has a structural formula (I) and disperse dye made from the monoazo thiazolotriazole disperse dye compound. A monoazo thiazolotriazole heterocyclic structure (3N1S) is introdu