23025-55-0

Usage

InChI:InChI=1/C8H10N2O2/c1-2-12-8(11)9-10-6-4-3-5-7-10/h3-7H,2H2,1H3/p+1

Upstream product

• 110-86-1 pyridine 
• 817-87-8 ethyl azidocarbonate 
• 6295-87-0 N-aminopyridin-1-ium iodide 
• 541-41-3 chloroformic acid ethyl ester 
• 84802-37-9 C₃₃H₃₂N₄O₆S 
• 17377-08-1 [1,2]diazepine-1-carboxylic acid ethyl ester 
• 66121-61-7 N,O-bistrimethylsilyl-N-(ethoxycarbonyl)hydroxylamine 

Downstream Products

• 30237-83-3 2-ethoxy-2-methoxy-4,5-diphenyl-2,3-dihydro-[1,3]oxazin-6-one 
• 30237-77-5 2-ethoxy-4,5-diphenyl-6H-1,3-oxazin-6-one 
• 36048-66-5 2-ethoxy-4,5-diphenyl-[1,3]oxazine-6-thione 
• 245-33-0 pyrido[1,2-b]indazole 
• 76426-79-4 (2-Pyridin-2-yl-phenyl)-carbamic acid ethyl ester 
• 110-86-1 pyridine 
• 16307-56-5 trans-1-ethoxycarbonyl-2-isopropyl-3-methylaziridine 
• 16307-56-5 cis-1-ethoxycarbonyl-2-isopropyl-3-methylaziridine 
• 58292-84-5 1-cyano-2-(p-tolylsulfonyl)-trans-stilbene 
• 84802-36-8 5,6-Diphenyl-3-(toluene-4-sulfonyl)-1H-pyrimidine-2,4-dione 
• 84802-35-7 2-Ethoxy-5,6-diphenyl-3-(toluene-4-sulfonyl)-3H-pyrimidin-4-one 
• 84802-37-9 C₃₃H₃₂N₄O₆S 
• 1311426-19-3 (Z)-dimethyl 2-(phenylacetamido)fumarate 

Relevant academic research and scientific papers

Stereo-controlled asymmetric bioreduction of α,β-dehydroamino acid derivatives

α,β-Dehydroamino acid derivatives proved to be a novel substrate class for ene-reductases from the 'old yellow enzyme' (OYE) family. Whereas N-acylamino substituents were tolerated in the α-position, β-analogues were generally unreactive. For aspartic aci

Azides: Part VII-Thermolysis of p-Toluenesulphonylazide and Ethyl Azidoformate in Pyridine and Its Derivatives; Evidence for an Electronic Equilibrium for N-Iminopyridinium Ylides

The thermolysis of p-toluenesulphonylazide and ethyl azidoformate in pyridine, ethyl isonicotinate and 2,6-dicarbethoxypyridine has been studied.Thermal rearrangement to the corresponding diazepines via a diazanorcardiene intermediate can not be achieved either by the application of positive nitrogen pressure or in the presence of several high boiling solvents.The detailed IR, PMR and X-ray photoelectron spectral analyses of the N-iminopyridinium ylides reveal a new electronic configuration for the ylides.

Reaction of N-(p-Tolylsulfonyl)diphenylcyclopropenimine with Pyridinium and Isoquinolinium Ylides

N-(p-Tolylsulfonyl)diphenylcyclopropenimine (2) reacted smoothly with pyridinium N-carbethoxyamide (3) to afford a new ylide (5), in addition to stilbene 4, uracil 6, and pyrimidone 7.An observed thermal transformation of 5 to 6 and 7 is discussed.Reaction of the cyanocarboethoxy methylides 15a-c with 2 produced the internal salts 16a-c, while the dicarbethoxy, monocarbethoxy, and benzoyl methylides 15d-f gave the pyridine-free cyclics 26, 28, and 29, respectively.The isoquinolinium methylides 31a-c reacted in an analogous fashion, while the N-amides 33a,b afforded cycloadducts 34a,b.A series of reactions used to correlate the structures of the latter is described, including an observed cycloaddition mode for diphenylcyclopropenone (1) with 33a-c which yielded 39, 37, and 42, respectively.

Synthesis of N-(Carbonylamino)-1,2,3,6-tetrahydropyridines with Analgesic, Antiinflammatory, and Hyperglycemic Activity

A group of N-(carbonylamino)-1,2,3,6-tetrahydropyridines was synthesized to investigate the effects that changes in functionality at the carbonyl group have on analgesic, antiinflammatory, and hyperglycemic activities.One of the most active analgesic comp

Investigation of Thermally Induced α-Deoxysilylation of Organosilylated Hydroxylamine Derivatives as a General Method for Nitrene Production

A variety of organosilylated hydroxylamine derivatives have been synthesized and studied as possible nitrene generators by thermally induced α-deoxysilylation: GN(OR')SiR3 GN + R'OSiR3, where G = EtO2C, ArCO, ArSO2, Me, H, and Ph2PO.The methods used to assess nitrene formation include trapping product characterization, substitutent variation, kinetic activation parameter measurements, Hammett studies, and solvent effects.While the latter two types of precursors were only briefly investigated because of their marked resistance to fragmentation, the combined data for the remaining compounds are consistent with the intermediacy of a nitrene.The existence of alternative deoxysilylation pathways is discussed in some cases, and for comparison with the nitrogen systems reported herein, kinetic activation parameters for α-deoxysilylation about carbon and silicon have been determined.