23028-24-2

Upstream product

• 552-41-0 1-(2-hydroxy-4-methoxyphenyl)ethanone 
• 108-24-7 acetic anhydride 
• 114-70-5 sodium phenylacetate 
• 103-80-0 phenylacetyl chloride 
• 63577-89-9 ethyl 2-phenyl-2,3-butadienoate 
• 151-10-0 1,3-Dimethoxybenzene 
• 75200-57-6 7-acetoxy-4-methyl-3-phenyl-2H-1-benzopyran-2-one 
• 103-82-2 phenylacetic acid 
• 2555-23-9 7-hydroxy-4-methyl-3-phenyl-chromen-2-one 
• 74-88-4 methyl iodide 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 42308-38-3 3-(2,4-dimethoxy-phenyl)-2-phenyl-crotonic acid 

Relevant academic research and scientific papers

Synthesis of substituted coumarins via Bronsted acid mediated condensation of allenes with substituted phenols or anisoles

Coumarins were obtained from the condensation of electron-rich arenes with allenes in the presence of TfOH in good yield. Depending on the substituent pattern of allenes employed, the general synthetic method of 4-substituted and 3,4-disubstituted 3-arylc

A novel one-step synthesis of 3-phenyl-, 4-methyl-3-phenyl- And3-phenyl-4-styrylcoumarins using DCC-DMSO

2-Hydroxybenzaldehydes 1 react with phenylacetic acid and its methoxy derivatives 2 in the presence of DCC in DMSO to afford 3-phenylcoumarins 3. Under identical conditions, 2-hydroxy-acetophenones 4 and 2'-hydroxychalcones 7 give rise to the corresponding 4-methyl-3-phenyl- and 3-phenyl-4-styrylcoumarins 6 and 8, respectively.