23047-08-7Relevant academic research and scientific papers
Alkenylation of 1-Acylindoles with Olefins Bearing Electron-withdrawing Substituents and Palladium Acetate
Itahara, Toshio,Ikeda, Mizue,Sakakibara, Tsutomu
, p. 1361 - 1363 (2007/10/02)
The oxidation of 1-(2,6-dichlorobenzoyl)indole with olefins, such as alkyl acrylates and acrylonitrile, and palladium acetate resulted in selective 3-alkenylation of the indole nucleus.Treatment of 1-acyl-3-methylindoles under similar conditions gave the corresponding 2-alkenyl substituted indoles, while the oxidation of 6-oxo-6H-isoindoloindole gave the corresponding 3-alkenyl substituted indoles.
A DIRECT N-ACYLATION OF INDOLE WITH CARBOXYLIC ACIDS
Terashima, Masanao,Fujioka, Masako
, p. 91 - 92 (2007/10/02)
A simple method for the N-acylation of indole is described.Indole (1) was directly acylated at nitrogen with various carboxylic acids (2) catalyzed by boric acid in moderate yield.
