230616-89-4

Upstream product

• 230616-86-1 4,4-diethoxy-1-p-tolyl-butane-1,3-dione 
• 558-13-4 carbon tetrabromide 
• 119518-09-1 1-(4-Methoxyphenyl)-5-(4-methylphenyl)pyrazol-3-ylcarboxaldehyde 

Downstream Products

• 230617-04-6 C₃₄H₂₇N₃O₆ 
• 230616-97-4 1-[1-(4-methoxy-phenyl)-5-p-tolyl-1H-pyrazol-3-yl]-pent-1-yn-3-ol 
• 230616-98-5 1-[1-(4-methoxy-phenyl)-5-p-tolyl-1H-pyrazol-3-yl]-4-methyl-pent-1-yn-3-ol 
• 230616-96-3 4-[1-(4-methoxy-phenyl)-5-p-tolyl-1H-pyrazol-3-yl]-but-3-yn-2-ol 
• 230616-95-2 3-[1-(4-methoxy-phenyl)-5-p-tolyl-1H-pyrazol-3-yl]-prop-2-yn-1-ol 
• 230616-92-9 3-bromoethynyl-1-(4-methoxy-phenyl)-5-p-tolyl-1H-pyrazole 

Relevant academic research and scientific papers

N-hydroxyurea and hydroxamic acid inhibitors of cyclooxygenase and 5- lipoxygenase

Two series of compounds (1 and 2) having structural features of the dual COX/5-LO inhibitor tepoxalin and the 5-LO inhibitor ABT-761 were prepared. Many of these hybrid compounds are potent COX and 5-LO inhibitors; two compounds (1a and 2t) inhibit eicosanoid biosynthesis in an ex vivo assay.