230637-98-6

Basic information

• Product Name: 1-(4-chlorophenyl)-4-hydroxy-3-isopropyl-6-(2-thienyl)-2(1H)-pyridinone
• Synonyms: 1-(4-chlorophenyl)-4-hydroxy-3-isopropyl-6-(2-thienyl)-2(1H)-pyridinone
• CAS NO: 230637-98-6
• Molecular Formula: C18H16ClNO2S
• Molecular Weight: 345.84314
• Mol File: 230637-98-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(4-chlorophenyl)-4-hydroxy-3-isopropyl-6-(2-thienyl)-2(1H)-pyridinone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-chlorophenyl)-4-hydroxy-3-isopropyl-6-(2-thienyl)-2(1H)-pyridinone(230637-98-6)
• EPA Substance Registry System: 1-(4-chlorophenyl)-4-hydroxy-3-isopropyl-6-(2-thienyl)-2(1H)-pyridinone(230637-98-6)

Safety Data

• Hazardous Substances Data: 230637-98-6(Hazardous Substances Data)

Upstream product

• 230637-87-3 2-(4-chloro-phenylamino)-2-thiophen-2-yl-propionitrile 
• 106-47-8 4-chloro-aniline 
• 88-15-3 2-Acetylthiophene 
• 15897-80-0 bis(2,4,6-trichlorophenyl) isopropylmalonate 
• 230637-90-8 (4-Chloro-phenyl)-[1-thiophen-2-yl-eth-(Z)-ylidene]-amine 

Relevant articles and documents

Synthesis and reactions of 4-hydroxy-2(1H)-pyridones with thienyl and pyridyl substituents in position 6 starting with azomethines and malonates

The reaction of 4 with substituted diethyl malonates 5a, or 'magic malonates' (bis-2,4,6-trichlorophenylmalonates 5b) leads to 4-hydroxy-2(1H)- pyridones 6. The azomethines 4 are prepared via the Strecker compounds 3 starting with methyl ketones 1, anilines, and potassium cyanide. Chlorination of pyridones 6 with sulfuryl chloride leads to compounds 7 while nitration gives 9.