230962-91-1Relevant academic research and scientific papers
Novel tricyclic benzothiazolo[2,3-c]thiadiazine antagonists of the platelet ADP receptor (P2Y12)
Scarborough, Robert M.,Laibelman, Alan M.,Clizbe, Lane A.,Fretto, Larry J.,Conley, Pamela B.,Reynolds, Elwood E.,Sedlock, David M.,Jantzen, Hans-Michael
, p. 1805 - 1808 (2001)
Novel non-nucleoside tricyclic platelet ADP receptor (P2Y12) antagonists have been discovered that bind reversibly and with high affinity to the platelet receptor. Condensation of various 2-aminobenzothiazoles with chlorosulfonylacetyl chloride
Platelet ADP receptor inhibitors
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Page column 18, (2008/06/13)
The invention relates to novel compounds of formula (I) containing fused heterocyclic ring systems which are effective platelet ADP receptor inhibitors: In formula (I), W is carbon or nitrogen, wherein at least one W is a carbon; and Y is nitrogen, oxygen, or sulfur. Such compounds including pharmaceutically acceptable salts are useful in various pharmaceutical compositions for the prevention and/or treatment of cardiovascular disease particularly those related to thrombosis.
