230964-35-9Relevant academic research and scientific papers
First total synthesis of the marine illudalane sesquiterpenoid alcyopterosin E.
Witulski, Bernhard,Zimmermann, Axel,Gowans, Nicholas D
, p. 2984 - 2985 (2002)
The first synthesis of the marine illudalane sesquiterpenoid alcyopterosin E was accomplished through a concise ABC ring-formation strategy using a rhodium(I)-catalysed intramolecular alkyne cyclotrimerisation as key connection.
Divergent total syntheses of five illudalane sesquiterpenes and assignment of the absolute configuration
Zeng, Zhixiong,Zhao, Yifan,Zhang, Yandong
supporting information, p. 4250 - 4253 (2019/05/01)
Concise, divergent total syntheses of five bioactive illudalane sesquiterpenes have been achieved. Our synthesis features an intermolecular [2+2+2] cycloaddition, and a lactone-directed aromatic C-H oxygenation to generate a temporary phenolic hydroxyl group which enables regioselective methylation. Furthermore, the absolute configuration of radulactone was assigned by chemical synthesis.
Silyl-cupration of an acetylene followed by ring-formation
Fleming, Ian,De Marigorta, Eduardo Martinez
, p. 889 - 900 (2007/10/03)
The acetylenes 1a-e undergo silyl-cupration followed by cyclisation, the acetylenes 1f-1h react with the silyl-cuprate reagent more rapidly at the alternative electrophilic site, and the acetylenes 1i, 1j and 17 give relatively low yields of cyclic produc
