230966-96-8Relevant articles and documents
Modulation of innate immune responses with synthetic lipid a derivatives
Zhang, Yanghui,Gaekwad, Jidnyasa,Wolfert, Margreet A.,Boons, Geert-Jan
, p. 5200 - 5216 (2008/02/04)
The lipid A moiety of lipopolysaccharides (LPS) initiates innate immune responses by interacting with Toll-like receptor 4 (TLR4), which results in the production of a wide range of cytokines. Derivatives of lipid A show potential for use as immuno-modula