23107-60-0Relevant academic research and scientific papers
Synthesis and biological evaluation of a new triazole-oxotechnetium complex
Martinage, Olivier,Le Clainche, Lo?c,Czarny, Bertrand,Dugave, Christophe
supporting information; experimental part, p. 6484 - 6490 (2012/09/08)
A new triazole oxotechnetium chelating agent was synthesized via a 'Click-to-Chelate' strategy. In vivo evaluation of the corresponding 99mTc complex shows that the tracer exhibits very interesting properties for molecular imaging.
Design and synthesis of a novel family of semi-rigid ligands: Versatile compounds for the preparation of 99mTc radiopharmaceuticals
Le Gal, Julien,Latapie, Laure,Gressier, Marie,Coulais, Yvon,Dartiguenave, Michele,Benoist, Eric
, p. 876 - 883 (2007/10/03)
Synthetic pathways to a range of novel semi-rigid tetradentate ligands, with sulfur, amido or amino donor groups, designed to coordinate technetium 99m have been developed. The technetium-99m complexes have been prepared and their stabilities in serum and
A simplified route to the synthesis of new 99mTc-specific tetradentate ligands
Le Gal, Julien,Benoist, Eric,Gressier, Marie,Coulais, Yvon,Dartiguenave, Michèle
, p. 9295 - 9297 (2007/10/03)
The synthesis of two new N2S2 or N2SO tetradentate ligands and the preparation of their technetium-99m complexes are reported. Each ligand leads to a unique 99mTc-complex with an excellent radiochemical yield. T
A synthetic analogue of the active site of Fe-containing nitrile hydratase with carboxamido N and thiolato S as donors: Synthesis, structure, and reactivities
Noveron,Olmstead,Mascharak
, p. 3247 - 3259 (2007/10/03)
As part of our work on models of the iron(III) site of Fe-containing nitrile hydratase, a designed ligand PyPSH4 with two carboxamide and two thiolate donor groups has been synthesized. Reaction of (Et4N)[FeCl4] with the d
Diagnostic radiopharmaceutical compounds (That)
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, (2008/06/13)
Tetradentate ligands are used to form neutral 99m-technetium complexes which may be useful as radiopharmaceuticals e.g. as brain imaging agents. The ligands have the structure STR1 where n is 2 or 3, m is 0-4, R is H or substituted or unsubstituted C1 -C6 alkyl, provided that one CR2 group adjacent the starred nitrogen atom represents CO and forms with the adjacent N atom, a --CONH-- amide group, Y is unsubstituted or substituted C1 -C6 alkyl, and one of X and X' represents H or a labile thiol protecting group while the other is unsubstituted or substituted C1 -C6 alkyl, alkenyl or alkynyl.
