23127-72-2Relevant academic research and scientific papers
Lewis-base-catalysed selective reductions of ynones with a mild hydride donor
Sch?mberg,Zi,Vilotijevic
supporting information, p. 3266 - 3269 (2018/04/05)
Ynones are efficiently reduced with a mild hydride donor in the presence of a catalytic amount of nucleophilic phosphines. The reactions are selective 1,2-reductions that give propargyl alcohols in yields of up to 96%. It is proposed that success in these reactions depends on the activation of ynones by a Lewis base catalyst. A protic additive plays a key role in suppressing the undesired reaction pathways and accelerating the 1,2-reductions.
Phosphonium Salts and Phosphoranes. Part 5. Thermal and Electron-Impact Induced Fragmentation of Heteroaroylmethylenetriphenylphosphoranes.
Brittain, Judith M.,Jones, R. Alan,Taheri, Sayed Ali Naghi
, p. 7609 - 7618 (2007/10/02)
A modification of Trippett's pyrolysis of aroylmethylenephosphoranes provides a general procedure for the synthesis of five-membered heteroarylethynes.The electron-impact induced fragmentation of the phosphoranes also produced ions corresponding in mass to the ethynes, but metastable ion data indicate that the extrusion of the ethyne follows the initial loss of H* from the molecular ion.
