23145-06-4

Usage

Uses

Given the hazardous nature of 5,7-Dichlorobenzofuran, its uses are primarily associated with the need for monitoring, regulation, and mitigation of its environmental impact.
Used in Environmental Monitoring:
5,7-Dichlorobenzofuran is used as a target for environmental monitoring programs to detect and quantify its presence in various ecosystems. This is crucial for assessing the extent of its contamination and the potential risks it poses to both human health and wildlife.
Used in Regulatory Efforts:
In regulatory frameworks, 5,7-Dichlorobenzofuran is used as a reference chemical in the development of policies and guidelines aimed at controlling its release into the environment. This includes setting permissible limits and implementing strategies to reduce emissions and waste disposal from industrial processes.
Used in Research and Development:
5,7-Dichlorobenzofuran serves as a subject for scientific research and development in the field of environmental chemistry and toxicology. Studies focus on understanding its behavior in the environment, its bioaccumulation potential, and the development of methods for its detection, degradation, and safe disposal.
Used in Public Health Initiatives:
Public health initiatives may utilize information about 5,7-Dichlorobenzofuran to educate the public on the risks associated with exposure to this chemical and to promote measures for personal protection and environmental stewardship.

InChI:InChI=1/C8H4Cl2O/c9-6-3-5-1-2-11-8(5)7(10)4-6/h1-4H

Upstream product

• 78830-79-2 (2,4-dichlorophenoxy)acetaldehyde diethyl acetal 
• 120-83-2 2,4-dichlorophenol 
• 2040-83-7 2,4-dichloro-6-iodophenol 
• 936840-15-2 C₈H₄Cl₂O 

Relevant academic research and scientific papers

Zeolite-catalyzed synthesis of 2,3-unsubstituted benzo[b]furans via the intramolecular cyclization of 2-aryloxyacetaldehyde acetals

An efficient and environmentally benign heterogeneous catalytic process for the synthesis of 2,3-unsubstituted benzo[b]furans has been established via the intramolecular cyclization of 2-aryloxyacetaldehyde acetals. By utilizing tin-exchanged H-β zeolite (Sn-β) as catalyst, a wide range of functionalized 2,3-unsubstituted benzo[b]furans could be prepared in good to excellent yields. The Sn-β zeolite catalyst also exhibited excellent shape selectivity on the cyclization of meta-substituted 2-aryloxyacetaldehyde acetals, and 6-substituted isomers were preferably formed up to 97% regio-selectivity. Moreover, Sn-β zeolite could be easily recovered and reused without any noticeable activity loss.

GLUCOSYLCERAMIDE SYNTHASE INHIBITORS FOR THE TREATMENT OF DISEASES

Described herein are compounds of Formula I, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or conditions associated with the enzyme glucosylceramide synthase (GCS).

Rhodium-catalyzed cycloisomerization: Formation of indoles, benzofurans, and enol lactones

(Chemical Equation Presented) Internal affairs: Indoles, benzofurans, and enol lactones are formed chemoselectively from the rhodium-catalyzed cyclo-isomerization reaction of easily prepared alkynyl aniline substrates (see scheme, cod = cycloocta-1,5-diene, DMF = N,N-dimethylformamide). The reaction may proceed by nucleophilic capture of a vinylidene intermediate. Indoles are formed under mild conditions using low catalyst loadings.