23145-06-4

Basic information

• Product Name: 5,7-Dichlorobenzofuran
• Synonyms: 5,7-Dichlorobenzofuran;Benzofuran, 5,7-dichloro-
• CAS NO: 23145-06-4
• Molecular Formula: C8H4 Cl2 O
• Molecular Weight: 187.02
• Mol File: 23145-06-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 248.1°C at 760 mmHg
• Flash Point: 103.9°C
• Appearance: /
• Density: 1.435g/cm³
• Vapor Pressure: 0.0389mmHg at 25°C
• Refractive Index: 1.627
• CAS DataBase Reference: 5,7-Dichlorobenzofuran(CAS DataBase Reference)
• NIST Chemistry Reference: 5,7-Dichlorobenzofuran(23145-06-4)
• EPA Substance Registry System: 5,7-Dichlorobenzofuran(23145-06-4)

Safety Data

• Hazardous Substances Data: 23145-06-4(Hazardous Substances Data)

Usage

General Description

5,7-Dichlorobenzofuran is an organic compound with the molecular formula C12H6Cl2O. It is a type of chlorinated benzofuran, which is a group of chemicals commonly found in industrial and environmental settings. 5,7-Dichlorobenzofuran is a known environmental contaminant and is considered a persistent organic pollutant due to its resistance to degradation. It is also a potential human carcinogen and has been linked to adverse health effects. This chemical can enter the environment through industrial processes, waste disposal, and emissions from combustion sources. It can bioaccumulate in the food chain, presenting a potential risk to human health and wildlife. Due to its hazardous nature, efforts are being made to monitor and regulate the presence of 5,7-Dichlorobenzofuran in the environment.

InChI:InChI=1/C8H4Cl2O/c9-6-3-5-1-2-11-8(5)7(10)4-6/h1-4H

Upstream product

• 78830-79-2 (2,4-dichlorophenoxy)acetaldehyde diethyl acetal 
• 120-83-2 2,4-dichlorophenol 
• 2040-83-7 2,4-dichloro-6-iodophenol 
• 936840-15-2 C₈H₄Cl₂O 

Relevant articles and documents

Zeolite-catalyzed synthesis of 2,3-unsubstituted benzo[b]furans via the intramolecular cyclization of 2-aryloxyacetaldehyde acetals

An efficient and environmentally benign heterogeneous catalytic process for the synthesis of 2,3-unsubstituted benzo[b]furans has been established via the intramolecular cyclization of 2-aryloxyacetaldehyde acetals. By utilizing tin-exchanged H-β zeolite (Sn-β) as catalyst, a wide range of functionalized 2,3-unsubstituted benzo[b]furans could be prepared in good to excellent yields. The Sn-β zeolite catalyst also exhibited excellent shape selectivity on the cyclization of meta-substituted 2-aryloxyacetaldehyde acetals, and 6-substituted isomers were preferably formed up to 97% regio-selectivity. Moreover, Sn-β zeolite could be easily recovered and reused without any noticeable activity loss.

Rhodium-catalyzed cycloisomerization: Formation of indoles, benzofurans, and enol lactones

(Chemical Equation Presented) Internal affairs: Indoles, benzofurans, and enol lactones are formed chemoselectively from the rhodium-catalyzed cyclo-isomerization reaction of easily prepared alkynyl aniline substrates (see scheme, cod = cycloocta-1,5-diene, DMF = N,N-dimethylformamide). The reaction may proceed by nucleophilic capture of a vinylidene intermediate. Indoles are formed under mild conditions using low catalyst loadings.