1,4-Naphthalenedione, 2-amino-3-(1-aziridinyl)-, also known as Mitomycin C, is an antineoplastic and antibiotic agent derived from Streptomyces caespitosus. It functions as a DNA cross-linking agent, inhibiting DNA replication and transcription, and is primarily used in the treatment of various cancers, including breast, stomach, lung, and pancreatic cancers. Mitomycin C is known for its ability to form covalent bonds between the two strands of DNA, leading to DNA damage and cell death. Its chemical consists structure of a naphthalene ring with a quinone group at positions 1 and 4, an amino group at position 2, and an aziridinyl group at position 3. This unique structure contributes to its potent anticancer activity and makes it an important drug in the field of oncology.
23152-88-7
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Basic information
- Product Name: 1,4-Naphthalenedione, 2-amino-3-(1-aziridinyl)-
- Synonyms:
- CAS NO:23152-88-7
- Molecular Formula: C12H10N2O2
- Molecular Weight:
- EINECS: N/A
- Product Categories: N/A
- Mol File: 23152-88-7.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 1,4-Naphthalenedione, 2-amino-3-(1-aziridinyl)-(CAS DataBase Reference)
- NIST Chemistry Reference: 1,4-Naphthalenedione, 2-amino-3-(1-aziridinyl)-(23152-88-7)
- EPA Substance Registry System: 1,4-Naphthalenedione, 2-amino-3-(1-aziridinyl)-(23152-88-7)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 23152-88-7(Hazardous Substances Data)
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Check Digit Verification of cas no
The CAS Registry Mumber 23152-88-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,1,5 and 2 respectively; the second part has 2 digits, 8 and 8 respectively.Calculate Digit Verification of CAS Registry Number 23152-88:
(7*2)+(6*3)+(5*1)+(4*5)+(3*2)+(2*8)+(1*8)=87
87 % 10 = 7
So 23152-88-7 is a valid CAS Registry Number.
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1,4-Naphthalenedione, 2-amino-3-(1-aziridinyl)-
