23156-68-5Relevant articles and documents
Identification of novel estrogen receptor (ER) agonists that have additional and complementary anti-cancer activities via ER-independent mechanism
Kim, Taelim,Kim, Hye-In,An, Ji-Young,Lee, Jun,Lee, Na-Rae,Heo, Jinyuk,Kim, Ji-Eun,Yu, Jihyun,Lee, Yong Sup,Inn, Kyung-Soo,Kim, Nam-Jung
, p. 1844 - 1848 (2016)
In this study, a series of bis(4-hydroxy)benzophenone oxime ether derivatives such as 12c, 12e and 12h were identified as novel estrogen receptor (ER) agonists that have additional and complementary anti-proliferative activities via ER-independent mechanism in cancer cells. These compounds are expected to overcome the therapeutic limitation of existing ER agonists such as estradiol and tamoxifen, which have been known to induce the proliferation of cancer cells.
O-ALKYL-BENZYLIDENEGUANIDINE DERIVATIVES AND THERAPEUTIC USE FOR THE TREATMENT OF DISORDERS ASSOCIATED AN ACCUMULATION OF MISFOLDED PROTEINS
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Page/Page column 65, (2016/01/25)
The present invention relates to a compound of formula (I), or a tautomer and/or a pharmaceutically acceptable salt thereof Formula (I), and its uses to treat a disorder associated with protein misfolding stress and in particular with an accumulation of m
Process for Preparing 2-Aminooxyethanol
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Page/Page column 3, (2010/03/31)
The invention relates to a process for preparing aminoglycol by reacting ketoximes with ethylene oxide under basic conditions to give a substituted 2-hydroxyethyl ketoxime and subsequently reacting the latter with an acid to give aminoglycol.