2316-61-2

Upstream product

• 2973-76-4 5-bromo-4-hydroxy-3-methoxybenzaldehyde 
• 121-33-5 vanillin 

Downstream Products

• 21709-81-9 3-Brom-4-hydroxy-5-methoxy-benzylchlorid 
• 137898-17-0 2-bromo-4-(hydroxymethyl)-6-methoxyphenyl trifluoromethanesulfonate 
• 23030-47-9 2-bromo-6-methoxycyclohexa-2,5-diene-1,4-dione 
• 2973-76-4 5-bromo-4-hydroxy-3-methoxybenzaldehyde 
• 474970-82-6 (5-bromo-4-(tert-butyldimethylsiloxy)-3-methoxybenzyloxy)-tert-butyldimethylsilane 
• 474970-83-7 (5-bromo-4-hydroxy-3-methoxybenzyloxy)-tert-butyldimethylsilane 
• 474970-87-1 [4-hydroxy-5-methoxy-3-(3',7'-dimethyl-2',6'-octadienyl)benzyloxy]-tert-butyldimethylsilane 
• 474970-81-5 4-hydroxy-3-methoxy-5-(3',7'-dimethyl-7'-hydroxy-6'-phenylselenyl-2'-octenyl)benzyl alcohol 
• 474970-89-3 [4-(tert-butyldimethylsiloxy)-5-methoxy-3-(3',7'-dimethyl-2',6'-octadienyl)benzyloxy]-tert-butyldimethylsilane 
• 474970-91-7 [4-(tert-butyldimethylsiloxy)-5-methoxy-3-(3',7'-dimethyl-6'-epoxy-2'-octenyl)benzyloxy]-tert-butyldimethylsilane 
• 474970-93-9 [4-(tert-butyldimethylsiloxy)-5-methoxy-3-(3',7'-dimethyl-7'-hydroxy-6'-phenylselenyl-2'-octenyl)benzyloxy]-tert-butyldimethylsilane 
• 137898-18-1 2-allyl-4-(hydroxymethyl)-6-methoxyphenyl trifluoromethanesulfonate 
• 887683-61-6 4-(1H-1,2,3-benzotriazol-1-ylmethyl)-2-bromo-6-methoxyphenol 

Relevant academic research and scientific papers

Approach to Merosesquiterpenes via Lewis Acid Catalyzed Nazarov-Type Cyclization: Total Synthesis of Akaol A

A Lewis acid catalyzed Nazarov-type cyclization of arylvinylcarbinol has been developed for the asymmetric synthesis of carbotetracyclic core of merosesquiterpenes. The reaction works only in the presence of 2 mol % of Sn(OTf)2 and Bi(OTf)3 in dichloroethane under elevated temperature. The methodology offers the synthesis of a variety of enantioenriched arylvinylcarbinols from commercially available (3aR)-sclareolide 9 in six steps with an eventual concise total synthesis of marine sesquiterpene quinol, akaol A (1a).

CATALYST COMPLEXES WITH CARBENE LIGAND AND METHOD FOR MAKING SAME AND USE IN METATHESIS REACTION

This invention relates to catalyst compounds and the synthesis and applications useful in olefin metathesis reactions. The catalyst compounds of the invention are represented by the formula (I): wherein M is a Group 8 metal; X1 and X2/sup

HIV INTEGRASE INHIBITORY OXOISOINDOLINE SULFONAMIDES

Novel oxoisoindoline sulfonamide integrase inhibitors are useful to inhibit HIV activity, and are therefore suitable for treatment or prophylaxis of HIV infection, for example in the treatment or prevention of AIDS. In particular embodiments, the inhibito

6,7-Dihydroxy-1-oxoisoindoline-4-sulfonamide-containing HIV-1 integrase inhibitors

Although an extensive body of scientific and patent literature exists describing the development of HIV-1 integrase (IN) inhibitors, Merck's raltegravir and Gilead's elvitegravir remain the only IN inhibitors FDA-approved for the treatment of AIDS. The em

A cascade cyclization approach to schweinfurthin B

(graph presented) A strategy for synthesis of the hexahydroxanthene moiety of the natural products schweinfurthin A, B, and D is described. The relative stereochemistry in the key cationic cyclization step is established through the preference of the phen

ON THE REGIOSELECTIVITY OF THE FREMY'S SALT OXIDATION OF PHENOLS

A detailed study of the regioselectivity of the Fremy's salt oxidation of phenols, including a series of MNDO calculations of the intermediate phenoxy radicals, has been carried out.The analysis of these results has led us to establish a new rule for the para vs. ortho regioselectivity, namely: "C-4 unsubstituted phenols, as well as phenols substituted at C-4 with easy-to-displace groups, undergo oxidation (or oxidative degradation) by the action of Fremy's salt, thus eventually providing the corresponding p-quinones".A similar rule for the ortho vs. ortho' regioselectivity could not be so precisely formulated since now steric effects play a significant major role.