2316-92-9

Usage

Uses

Used in Food Industry:
4-(2,2-Dimethylpropyl)-phenol is used as a preservative in the food industry to prevent the oxidation and spoilage of food products. It helps maintain the freshness and quality of the food by inhibiting the formation of free radicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-(2,2-Dimethylpropyl)-phenol is used as an antioxidant to protect medications from degradation and extend their shelf life. It helps maintain the stability and efficacy of pharmaceutical products.
Used in Rubber Products:
4-(2,2-Dimethylpropyl)-phenol is used in the rubber industry as an antioxidant to prevent the oxidation and degradation of rubber materials. It helps improve the durability and performance of rubber products.
Used in Cosmetics and Personal Care Products:
4-(2,2-Dimethylpropyl)-phenol has been found to have potential benefits for skin health and has been used in some cosmetics and personal care products. It may help protect the skin from oxidative stress and support skin health.
However, it is important to note that there have been some concerns about the potential health risks associated with 4-(2,2-Dimethylpropyl)-phenol, including its potential to act as an endocrine disruptor and its association with certain health conditions. As a result, its use in various applications may be subject to regulatory restrictions and safety assessments.

InChI:InChI=1/C11H16O/c1-11(2,3)8-9-4-6-10(12)7-5-9/h4-7,12H,8H2,1-3H3

Upstream product

• 123-08-0 4-hydroxy-benzaldehyde 
• 52986-52-4 4-(2,2-dimethylpropyl)benzaldehyde 
• 258503-99-0 4-neopentyl-benzenesulfonic acid 
• 106-44-5 p-cresol 
• 558-17-8 tert-Butyl iodide 

Downstream Products

• 653578-47-3 2-chloro-4-neopentylphenol 
• 1349842-17-6 4-hydroxy-4-neopentylcyclohexa-2,5-dienone 
• 1349842-19-8 tert-butyl (1-neopentyl-4-oxocyclohexa-2,5-dien-1-yl) malonate 
• 860616-44-0 1-(3-bromo-propoxy)-2-chloro-4-(2,2-dimethyl-propyl)-benzene 

Relevant academic research and scientific papers

SUBSTITUTED PHENOXYMETHYL DIHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF

The present invention relates to a series of substituted phenoxymethyl dihydro oxazolopyrimidinones of formula (I) defined herein. This invention also relates to methods of making these compounds including novel intermediates. The compounds of this invent

Regioselective and stereoselective cyclizations of cyclohexadienones tethered to active methylene groups

The cyclization of 2,5-cyclohexadienones tethered to activated methylene groups was studied. The substitution around the cyclohexadienone ring serves to regioselectively direct these cyclizations based primarily on electronic effects. In the case of brominated substrates, these reactions proceed to give highly unusual electron-deficient tricyclic cyclopropanes. By using a Cinchona alkaloid-based phase-transfer catalyst, prochiral cyclohexadienones can be desymmetrized with moderate stereoselectivity.

COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY

The present invention provides compounds of Formula (I) (wherein R1, R3, X, W, Z and ring Y are as defined herein). The present invention also provides compositions comprising these compounds that are useful for treating cellular proliferative diseases or disorders associated with KSP kinesin activity and for inhibiting KSP kinesin activity.

(2R)-2-Methylchromane-2-carboxylic acids: Discovery of selective PPARα agonists as hypolipidemic agents

A SAR study was conducted on chromane-2-carboxylic acid toward selective PPARα agonisim. As a result, highly potent, and selective PPARα agonists were discovered. The optimized compound 43 exhibited robust lowering of total cholesterol levels in hamster and dog animal models.

Preparation and Reactions of Dianions from the Cresols

With n-BuLi/KO-t-Bu, protons are removed from the hydroxyl and methyl groups of cresols 5 to give dianions 6 in yields of 85percent (ortho), 95percent (meta), and 42percent (para).These dianions react with alkyl halides, Me3SiCl, Bu3SnCl, CO2, and oxidizing agents at carbon only and with dialkyl sulfates at both carbon and oxygen.Thus phenol derivatives bearing primary alkyl groups can be prepared from the corresponding methylphenols via dianions 6.