23160-08-9

Basic information

• Product Name: 5-(2-fluoro-benzylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione
• Synonyms: 5-(2-fluoro-benzylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione
• CAS NO: 23160-08-9
• Molecular Weight: 250.226
• Mol File: 23160-08-9.mol

Chemical Properties

• CAS DataBase Reference: 5-(2-fluoro-benzylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2-fluoro-benzylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione(23160-08-9)
• EPA Substance Registry System: 5-(2-fluoro-benzylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione(23160-08-9)

Safety Data

• Hazardous Substances Data: 23160-08-9(Hazardous Substances Data)

Upstream product

• 2033-24-1 cycl-isopropylidene malonate 
• 446-52-6 2-Fluorobenzaldehyde 

Downstream Products

• 1147856-08-3 5-(1-(2-fluorophenyl)but-3-enyl)-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 1415414-27-5 1,2-bis[3-cyano-4-(2-fluorophenyl)-6-oxo-1,4,5,6-tetrahydropyridin-2-yl]diselane 
• 1415414-30-0 2-[3-cyano-4-(2-fluorophenyl)-6-oxo-1,4,5,6-tetrahydropyridin-2-ylselanyl]-N-phenylacetamide 
• 1415414-28-6 2-(ethylselanyl)-4-(2-fluorophenyl)-6-oxo-1,4,5,6-tetrahydropyridine-3-carbonitrile 
• 1415414-29-7 4-(2-fluorophenyl)-2-{[2-(4-methylphenyl)-2-oxoethyl]selanyl}-6-oxo-1,4,5,6-tetrahydropyridine-3-carbonitrile 

Relevant articles and documents

Synthesis of new guanidium-meldrum acid zwitterionic salts and dynamic NMR study of rotational energy barrier around C-NH bond of guanidine moiety

Synthesis of the Guanidium-Meldrum acid zwitterionic salts was developed through a three component reaction of 2, 2-dimethyl-1, 3-dioxane-4, 6-dione (Meldrum acid), aromatic aldehydes and N, N, N', N'- Tetramethyl-guanidine in benzen at room temperature.

Sc(OTf)3-catalyzed conjugate allylation of alkylidene meldrum's acids

Alkylidene Meldrum's acids are allylated in a conjugate fashion by allyltin nucleophiles under mild Sc(OTf)3-catalyzed conditions. The addition is functional group tolerant and reactions with nonracemic alkylidenes are highly diastereoselective

A general and practical preparation of alkylidene Meldrum's acids

Although many methods have been reported for the Knoevenagel condensation of aldehydes and Meldrum's acid, most are not general or use unconventional reagents and conditions. We have found that alkylidene Meldrum's acids form readily in benzene solution u