231615-34-2

Upstream product

• 122376-70-9 (2-Fluoro-phenyl)-pyridin-2-yl-acetonitrile 
• 231615-13-7 2-(2-Fluoro-phenyl)-2-pyridin-2-yl-acetamide 
• 231615-22-8 4-(2-fluoro-phenyl)-pyrido[1,2-c]pyrimidine-1,3-dione 

Downstream Products

• 532427-82-0 2-(4-bromo-butyl)-4-(2-fluoro-phenyl)-5,6,7,8-tetrahydro-pyrido[1,2-c]pyrimidine-1,3-dione 

Relevant academic research and scientific papers

Synthesis and structure of novel 4-arylhexahydro-1h,3h-pyrido[1,2- c]pyrimidine derivatives

A series of new 4-aryl-hexahydro-IH,3H-pyrido[1,2-c]pyrimidine-1,3- dione derivatives 4a-k were prepared by catalytic hydrogenation of 4-aryl- 1H,2H-pyrido[1,2-c]pyrimidine-1,3-diones 3a-k. The structures of compounds were determined by 1H and 13C nmr spectroscopy in solution. Steric hindrance caused twisting of the phenyl ring with respect to the pyridopyrimidine system, the effect was confirmed by X-ray diffraction.