231622-04-1

Basic information

• Product Name: 2-CarboxyMethoxyMethyl-pyrrolidine-1-carboxylic acid tert-butyl ester
• Synonyms: 2-CarboxyMethoxyMethyl-pyrrolidine-1-carboxylic acid tert-butyl ester;2-(1-(tert-Butoxycarbonyl)pyrrolidin-2-yl)-2-Methoxyacetic acid
• CAS NO: 231622-04-1
• Molecular Formula: C12H21NO5
• Molecular Weight: 259.29884
• Mol File: 231622-04-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-CarboxyMethoxyMethyl-pyrrolidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CarboxyMethoxyMethyl-pyrrolidine-1-carboxylic acid tert-butyl ester(231622-04-1)
• EPA Substance Registry System: 2-CarboxyMethoxyMethyl-pyrrolidine-1-carboxylic acid tert-butyl ester(231622-04-1)

Safety Data

• Hazardous Substances Data: 231622-04-1(Hazardous Substances Data)

Upstream product

• 1018826-65-7 (R)-tert-butyl 2-((2-(tert-butoxy)-2-oxoethoxy)methyl)pyrrolidine-1-carboxylate 
• 69610-40-8 N-(tert-butoxycarbonyl)-L-prolinol 
• 132127-47-0 ethyl (2'S)-4-(N-(tert-Butoxycarbonyl)pyrrolidin-2'-yl)-3-oxabutanoate 

Relevant articles and documents

SUBSTITUTED SULFONAMIDE COMPOUNDS

Substituted sulfonamide derivatives, a process for their preparation, pharmaceutical compositions containing these compounds, and to the use of substituted sulfonamide derivatives in the treatment or inhibition of pain and/or various disorders or disease states.

Compounds with growth hormone releasing properties

There are disclosed novel synthetic peptides of the general formula (I) Compounds of formula (I) stimulate the release of growth hormone from the pituitary in humans and animals. A method for increasing the rate and extent of growth of animals to increase their milk and wool production or for the treatment of ailments, and the use of the compounds of formula (I) for the preparation of medicaments, are also disclosed.

Compounds with growth hormone releasing properties

Compounds of the general formula I STR1 compositions containing them, and their use for treating medical disorders resulting from a deficiency in growth hormone are described.

Compounds with growth hormone releasing properties

Novel peptide derivatives, compositions containing them, and their use for treating medical disorders resulting from a deficiency in growth hormone are disclosed. The peptides have the formula (I): STR1 wherein a, b, A, R1, L1, D, R3, R4, R2, L2, E and G are as defined in the specification. These peptides exhibit improved resistance to proteolytic degradation, and hence, improved bioavailability.

Synthesis and in vitro characterization of new growth hormone secretagogues derived from ipamorelin with dipeptidomimetic N-terminals

The structural requirements for N-terminal features for the minimal structure of growth hormone secretagogues derived from ipamorelin are investigated. It is found, that incorporation of nonpolar peptidomimetic amino acids at the N-terminal can replace the Aib-His moiety and lead to compounds with high in vitro potency with respect to their growth hormone secretagogue properties. New unnatural amino acids with double bonds, ether- linkages, and 1,3-phenylene-moieties in the backbone proved to be valuable dipeptidomimetics. Using them, growth hormone secretagogues with high potencies were obtained.