231622-39-2

Basic information

• Product Name: 2-[4-[3-(4-Fluorophenyl)pyrrolidin-1-yl]butyl]-1H-benzisothiazol-3(2H)-one 1,1-dioxide
• Synonyms: LB-50053
• CAS NO: 231622-39-2
• Molecular Formula: C₂₁H₂₃FN₂O₃S
• Molecular Weight: 402.49146
• Mol File: 231622-39-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[4-[3-(4-Fluorophenyl)pyrrolidin-1-yl]butyl]-1H-benzisothiazol-3(2H)-one 1,1-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[4-[3-(4-Fluorophenyl)pyrrolidin-1-yl]butyl]-1H-benzisothiazol-3(2H)-one 1,1-dioxide(231622-39-2)
• EPA Substance Registry System: 2-[4-[3-(4-Fluorophenyl)pyrrolidin-1-yl]butyl]-1H-benzisothiazol-3(2H)-one 1,1-dioxide(231622-39-2)

Safety Data

• Hazardous Substances Data: 231622-39-2(Hazardous Substances Data)

Upstream product

• 220474-60-2 1-benzyl-3-(4'-fluorophenyl)pyrrolidine 
• 1493-23-8 (4-fluorophenyl)lithium 
• 103564-59-6 N-[4-bromobutyl]saccharin 
• 144620-11-1 3-(4-fluorophenyl)pyrrolidine 

Relevant articles and documents

N-Substituted-3-arylpyrrolidines: Potent and Selective Ligands at Serotonin 1A Receptor

3-Arylpyrrolidines are synthesized through the coupling of N-benzyl-3-(methanesulfonyloxy)pyrrolidine with diarylcuprates. Pharmacological evaluation of a series of N-substituted-3-arylpyrrolidines toward several neurotransmitter receptors indicated that some of them are good ligands for serotonin 1A receptor. Particularly, N-pyrrolidines were found to be potent and selective ligands. A preliminary biological evaluation for several selected compounds indicated that they are potentially effective antianxiety and antidepressant agents.