231947-67-4Relevant academic research and scientific papers
Cyclopalladation of mono-, di- and tribenzylamine by palladium(II) acetate Influence of bulkiness around the nitrogen atom of benzylamine upon internal metallation
Fuchita, Yoshio,Yoshinaga, Kazuhiko,Hanaki, Tomoko,Kawano, Hiroyuki,Kinoshita-Nagaoka, Junko
, p. 273 - 281 (2007/10/03)
Cyclopalladation of mono-, di- and tribenzylamine has been investigated by reacting the corresponding amines with an equimolar amount of palladium(II) acetate (reaction i), or by heating the corresponding bis-amine complexes [Pd(O2CMe)2{(PhCH2)nNH 3-n}2] (n = 1, 2) (reaction ii). By the reaction i, all the three amines undergo cyclopalladation. However, in the case of the reaction ii, only the dibenzylamine complex [Pd(O2CMe)2 {(PhCH2)2NH}2] has been converted into a cyclopalladated complex. The reactivity of the three benzylamines towards Cyclopalladation has been discussed in terms of the co-ordinating ability influenced by the bulkiness around the nitrogen atom. Temperature-dependent 1H-NMR spectra are observed for mononuclear cyclopalladated complexes [Pd(O2CMe){C6H4CH2N(CH 2Ph)2-C1, N} (L = PPh3, AsPh3) and are attributed to the dissociation of the nitrogen atom in the cyclopalladated chelate ring. A heteroleptic bis-cyclopalladated complex [Pd[C6H4CH2N(CH2Ph) 2-C1, N](C6H4CH2NMe2-C1, N)] has also been prepared. X-ray crystallographic studies on [{Pd(O2CMe)[C6H4CH2N(CH 2Ph)2-C1, N]}2] and [Pd[C6H4CH2N(CH2Ph) 2-C1, N](C6H4CH2NMe2-C1, N)] have been reported.
