23197-53-7

Basic information

• Product Name: 4-HYDROXY-2'-METHYLDIPHENYLAMINE
• Synonyms: 4-O-TOLYLAMINO-PHENOL;4-HYDROXY-2'-METHYLDIPHENYLAMINE;2'-METHYL-4-HYDROXY DIPHENYL AMINE;2-Methyl-4'-hydroxydianiline
• CAS NO: 23197-53-7
• Molecular Formula: C₁₃H₁₃NO
• Molecular Weight: 199.25
• Mol File: 23197-53-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 334.8°C at 760 mmHg
• Flash Point: 131.6°C
• Appearance: /
• Density: 1.17g/cm³
• Vapor Pressure: 6.43E-05mmHg at 25°C
• Refractive Index: 1.653
• CAS DataBase Reference: 4-HYDROXY-2'-METHYLDIPHENYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-HYDROXY-2'-METHYLDIPHENYLAMINE(23197-53-7)
• EPA Substance Registry System: 4-HYDROXY-2'-METHYLDIPHENYLAMINE(23197-53-7)

Safety Data

• Hazardous Substances Data: 23197-53-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H13NO/c1-10-4-2-3-5-13(10)14-11-6-8-12(15)9-7-11/h2-9,14-15H,1H3

Upstream product

• 123-31-9 hydroquinone 
• 95-53-4 o-toluidine 
• 95-49-8 2-methylchlorobenzene 
• 123-30-8 4-amino-phenol 
• 95-46-5 2-methylphenyl bromide 
• 16419-60-6 2-Methylphenylboronic acid 

Downstream Products

• 66311-46-4 N⁴-(2-methylphenyl) benzene-1,4-diamine 
• 260-94-6 acridine 
• 92-81-9 acridine 
• 123-31-9 hydroquinone 
• 95-53-4 o-toluidine 
• 107613-48-9 (4-ethoxy-phenyl)-o-tolyl-amine 

Relevant articles and documents

Substituted anilino-benzothiazole-2-thioketone compound as well as preparation method and application thereof

The invention discloses a substituted anilino-benzothiazole-2-thioketone compound and a preparation method thereof. In addition, the invention also relates to an application of the compound in rubberproducts. The substituted anilino-benzothiazole-2-thioketone compound disclosed by the invention not only can promote rubber vulcanization, but also can prolong the service life of the rubber products.

Orthogonal Cu- and Pd-based catalyst systems for the O- and N-arylation of aminophenols

O- or N-arylated aminophenol products constitute a common structural motif in various potentially useful therapeutic agents and/or drug candidates. We have developed a complementary set of Cu- and Pd-based catalyst systems for the selective O- and N-arylation of unprotected aminophenols using aryl halides. Selective O-arylation of 3- and 4-aminophenols is achieved with copper-catalyzed methods employing picolinic acid or CyDMEDA, trans-N,N′-dimethyl-1,2- cyclohexanediamine, respectively, as the ligand. The selective formation of N-arylated products of 3- and 4-aminophenols can be obtained with BrettPhos precatalyst, a biarylmonophosphine-based palladium catalyst. 2-Aminophenol can be selectively N-arylated with CuI, although no system for the selective O-arylation could be found. Coupling partners with diverse electronic properties and a variety of functional groups can be selectively transformed under these conditions.