23205-66-5 Usage
Uses
Used in Pharmaceutical Industry:
2',3',5'-TRI-O-ACETYL-8-FLUORO ADENOSINE is used as a precursor in the synthesis of antiviral and anticancer drugs due to its potential to modulate cellular processes and target specific enzymes and receptors.
Used in Antiviral Drug Development:
In the field of antiviral research, 2',3',5'-TRI-O-ACETYL-8-FLUORO ADENOSINE is utilized as a key component in the development of new antiviral agents, leveraging its ability to interfere with viral replication and associated cellular pathways.
Used in Anticancer Drug Development:
2',3',5'-TRI-O-ACETYL-8-FLUORO ADENOSINE is employed as a building block in the creation of novel anticancer medications, capitalizing on its potential to target and disrupt cancerous cell processes, thereby inhibiting tumor growth and progression.
Used in Biochemical Research:
2',3',5'-TRI-O-ACETYL-8-FLUORO ADENOSINE is also used as a research tool in biochemical studies to investigate the mechanisms of action of adenosine and its derivatives, providing insights into the development of targeted therapies for various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 23205-66-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,2,0 and 5 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 23205-66:
(7*2)+(6*3)+(5*2)+(4*0)+(3*5)+(2*6)+(1*6)=75
75 % 10 = 5
So 23205-66-5 is a valid CAS Registry Number.
23205-66-5Relevant academic research and scientific papers
Barrio, Jorge R.,Namavari, Mohammad,Phelps, Michael E.,Satyamurthy, Nagichettiar
, p. 10408 - 10411 (1996)
An efficient regiocontrolled approach to the synthesis of 8-fluoropurines by direct fluorination of purines with dilute elemental fluorine is described. The one-step procedure produced regiospecific substitution of the C(8)-hydrogen of purine derivatives in isolated yields close to 30% with protected purines in CHCl3. Fluorination yields with unprotected purines in EtOH were reduced to less than 10%. The electrophilic fluorination procedure has a broad scope of applicability and permits a ready and easy access to 8-fluoropurine derivatives, for the first time, for evaluation of their biochemical and pharmacological properties.
Process for producing 8-fluoropurines
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, (2008/06/13)
An efficient, regiocontrolled approach to the synthesis of 8-fluoropurines by direct fluorination of purines with dilute elemental fluorine, or acetyl hypofluorite, is provided. In a preferred embodiment, a purine compound is dissolved in a polar solvent and reacted with a dilute mixture of F2 in He or other inert gas.
