23211-59-8Relevant academic research and scientific papers
Simplifying pyridoxal: Practical methods for amino acid dynamic kinetic resolution
Felten, Albert E.,Zhu, Gangguo,Aron, Zachary D.
, p. 1916 - 1919 (2010)
Figure presented Metal complexes of picolinaldehyde are identified as low-cost and environmentally benign catalysts, providing high reaction rates and turnovers for the racemization of amino acids. These pyridoxal surrogates demonstrate activity toward a variety of amino acid esters. Applications to chemoenzymatic dynamic kinetic resolutions provide access to amino acids in high yields and with excellent enantioselectivities, demonstrating their compatibility with protease-mediated transformations.
