232267-03-7Relevant articles and documents
Synthesis of ethynyl-3-hydroxyquinoline-4-carboxylic acids
Maklakova, S. Yu.,Chuprov,Mazhuga,Beloglazkina,Zyk,Majouga
, p. 1460 - 1461 (2019)
3-Hydroxyquinoline-4-carboxylic acids containing ethynyl moiety in the 6th and 8th positions were obtained for the fi rst time. A synthetic approach to aforementioned compounds based on the Sonogashira cross-coupling and the Pfi tzinger reaction was devel
Process for the synthesis of compounds for selectin inhibition
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Page/Page column 11-12, (2010/11/26)
The present teachings relate to the field of anti-inflammatory substances, and more particularly to the preparation of compounds that act as antagonists of the mammalian adhesion proteins known as selecting. In some embodiments, the present teachings prov
Novel 3-aryl-2,5-dihydroxy-1,4-benzoquinone derivatives, their preparation method and pharmaceutical compositions containing same
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Page/Page column 5, (2008/06/13)
Compound of formula (I): wherein: R1 and R2, which may be identical or different, each represents hydrogen, acyl or alkyl, Ar represents aryl or heteroaryl, A represents a group selected from: R4 represents hydrogen or alk
Chemocontrolled reduction of α-keto esters by hydrides: A possible solution for selective reduction of the ester function
Dalla,Catteau
, p. 6497 - 6510 (2007/10/03)
α-keto primary alcohols or α-silyloxy ketones have been obtained with a high level of selectivity from enolic α-keto esters in two steps, with the reduction of the α-silyloxy α,β-unsaturated ester by LiAlH4 as the key step. The methodology developed in this work represents a 'reversed' chemoselective reduction of the ester group instead of the keto of an enolic α-keto ester due to a one-pot sequential ester reduction-desilylation or silyl migration process.
