232273-85-7Relevant academic research and scientific papers
Syntheses of cyclobutane derivatives: Total synthesis of (+) and (-) enantiomers of the oleander scale Aspidiotus nerii sex pheromone
Boyer, Francois-Didier,Ducrot, Paul-Henri
, p. 1201 - 1211 (1999)
Synthesis of both enantiomers of the Aspidiotus nerii sex pheromone and their diastereomers has been achieved using, as a key step, an intramolecular ester enolate alkylation reaction for the formation of the cyclobutane ring with a good control of the relative configurations of the asymmetric centers. Stereoselective synthesis of a number of other trisubstituted cyclobutane derivatives also proves the versatility of the methodology used for the synthesis of the Aspidiotus nerii sex pheromone.
