232276-00-5 Usage
Uses
Used in Pharmaceutical Development:
Ethyl (S)-2-amino-3-(4-bromophenyl) propanoate hydrochloride is used as a prodrug in pharmaceutical development for its potential to be converted into an active drug within the body. Its unique chemical structure allows for targeted drug delivery and treatment of various conditions.
Used in Neurological Disorders Treatment:
In the field of neurology, Ethyl (S)-2-amino-3-(4-bromophenyl) propanoate hydrochloride is utilized as a therapeutic agent for the treatment of neurological disorders. Its ability to modulate neurotransmitter levels and receptor activities makes it a promising candidate for managing conditions such as Parkinson's disease, Alzheimer's disease, and epilepsy.
Used in Mental Health Treatment:
Ethyl (S)-2-amino-3-(4-bromophenyl) propanoate hydrochloride is employed as a pharmaceutical compound in the treatment of mental health issues. Its potential to influence neurotransmitter pathways and modulate mood-related chemicals in the brain positions it as a candidate for the management of depression, anxiety, and other mood disorders.
Used in Pain Management:
In the pain management industry, Ethyl (S)-2-amino-3-(4-bromophenyl) propanoate hydrochloride is used as an analgesic agent. Its capacity to interact with pain receptors and pathways can provide relief from acute and chronic pain conditions, making it a valuable asset in the development of novel pain relief medications.
Used in Chemical Research:
Ethyl (S)-2-amino-3-(4-bromophenyl) propanoate hydrochloride serves as a key compound in chemical research, where it is used to study the structure-activity relationships of prodrugs and their conversion to active pharmaceutical agents. Its unique properties make it an important tool for understanding the mechanisms of drug action and the development of new therapeutic strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 232276-00-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,3,2,2,7 and 6 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 232276-00:
(8*2)+(7*3)+(6*2)+(5*2)+(4*7)+(3*6)+(2*0)+(1*0)=105
105 % 10 = 5
So 232276-00-5 is a valid CAS Registry Number.
232276-00-5Relevant academic research and scientific papers
Discovery and characterization of an inhibitor of glucosylceramide synthase
Richards, Steven,Larson, Christopher J.,Koltun, Elena S.,Hanel, Art,Chan, Vicky,Nachtigall, Jason,Harrison, Amanda,Aay, Naing,Du, Hongwang,Arcalas, Arlyn,Galan, Adam,Zhang, Jeff,Zhang, Wentao,Won, Kwang-Ai,Tam, Danny,Qian, Fawn,Wang, Tao,Finn, Patricia,Ogilvie, Kathy,Rosen, Jon,Aoyama, Ron,Plonowski, Artur,Cancilla, Belinda,Bentzien, Frauke,Yakes, Michael,Mohan, Raju,Lamb, Peter,Nuss, John,Kearney, Patrick
experimental part, p. 4322 - 4335 (2012/06/30)
Targeting glycosphingolipid synthesis has emerged as a novel approach for treating metabolic diseases. 32 (EXEL-0346) represents a new class of glucosylceramide synthase (GCS) inhibitors. This report details the elaboration of hit 8 with the goal of achieving and maintaining maximum GCS inhibition in vivo. 32 inhibited GCS with an IC50 of 2 nM and achieved maximum hepatic GCS inhibition after four or five daily doses in rodents. Robust improvements in glucose tolerance in DIO mice and ZDF rats were observed after 2 weeks of q.d. dosing. Four weeks of dosing resulted in decreased plasma triglycerides and reduced hepatic fat deposition. Thus, 32 provides insight into the amount of metabolic regulation that can be restored following achievement of maximal target knockdown.
