232276-45-8

Basic information

• Product Name: N-(2,6-dichlorobenzoyl)-O-(trifluoromethanesulfonyl)-L-tyrosine methyl ester
• Synonyms: N-(2,6-dichlorobenzoyl)-O-(trifluoromethanesulfonyl)-L-tyrosine methyl ester
• CAS NO: 232276-45-8
• Molecular Weight: 500.279
• Mol File: 232276-45-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(2,6-dichlorobenzoyl)-O-(trifluoromethanesulfonyl)-L-tyrosine methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2,6-dichlorobenzoyl)-O-(trifluoromethanesulfonyl)-L-tyrosine methyl ester(232276-45-8)
• EPA Substance Registry System: N-(2,6-dichlorobenzoyl)-O-(trifluoromethanesulfonyl)-L-tyrosine methyl ester(232276-45-8)

Safety Data

• Hazardous Substances Data: 232276-45-8(Hazardous Substances Data)

Upstream product

• 938195-80-3 methyl N-(2,6-dichlorobenzoyl)-L-tyrosinate 
• 358-23-6 trifluoromethylsulfonic anhydride 

Downstream Products

• 959992-69-9 methyl 4-({2-[(tert-butoxycarbonyl)(methyl)amino]quinolin-7-yl}methyl)-N-[(2,6-dichlorophenyl)carbonyl]-L-phenylalaninate 
• 959991-55-0 methyl 4-(4-aminopiperidin-1-yl)-N-(2,6-dichlorobenzoyl)-L-phenylalaninate 
• 938195-81-4 methyl 4-[1-(tert-butoxycarbonyl)-1,2,3,6-tetrahydropyridin-4-yl]-N-(2,6-dichlorobenzoyl)-L-phenylalaninate 
• 232276-58-3 N-(2,6-dichlorobenzoyl)-4-[4-(1,3-dioxolan-2-yl)-2,6-dimethoxyphenyl]-L-phenylalanine methyl ester 
• 232276-67-4 N-(2,6-dichlorobenzoyl)-4-(2-cyano-thien-3-yl)-L-phenylalanine methyl ester 
• 959992-08-6 4-{(2S)-2-[(2,6-dichlorobenzoyl)amino]-3-methoxy-3-oxopropyl}benzoic acid 
• 959991-54-9 methyl 4-{4-[(tert-butoxycarbonyl)amino]piperidin-1-yl}-N-(2,6-dichlorobenzoyl)-L-phenylalaninate 

Relevant articles and documents

Rh-catalyzed aerobic oxidative cyclization of anilines, alkynes, and CO

Transition-metal-catalyzed oxidative C-H cyclization of anilines has been an attractive and powerful strategy for the efficient construction of N-heterocycles. However, primary and tertiary anilines are rarely employed in this strategy due to the relative instability with strong oxidants or the presence of three C-N bonds. We describe here a novel Rh-catalyzed C-H cyclization of a wide range of anilines with alkynes and CO, using an aerobic oxidative protocol. Particularly, the simple primary anilines and readily prepared tertiary anilines could be easily converted to quinolin-2(1H)-ones, which are high value-added, biologically significant N-heterocycles, via C-N bond cleavage.