23231-18-7Relevant academic research and scientific papers
Gem-dichloro(alkyl)cyclopropanes in reactions with NOCl?2SO 3: Synthesis of alkyl-5-chloroisoxazoles
Zyk,Bondarenko,Gavrilova,Chizhov,Zefirov
, p. 328 - 333 (2011)
Nitrosation of gem-dichloro(alkyl)cyclopropanes with the complex NOCl?2SO3 gave regioisomeric alkyl-5-chloroisoxazoles in high yields; a similar reaction with 1,2-bis(gem-dichlorocyclopropyl)ethane afforded the corresponding bis(5-chloroisoxazoles). The reactivities of gem-dichlorobicyclo[n.1.0]alkanes depend on their spatial structures, sharply decreasing with an increase in the number of the methylene units in the bicyclic molecule.
