23271-18-3Relevant academic research and scientific papers
Three-Component Synthesis of Quinolines Based on Radical Cascade Visible-Light Photoredox Catalysis
Choi, Jun-Ho,Park, Cheol-Min
supporting information, p. 3553 - 3562 (2018/09/22)
Synthesis of highly substituted quinolines has been developed based on three-component radical cascade based on visible-light photoredox catalysis. This tandem coupling reaction has been coordinated to proceed with high chemoselectivity based on the differential electronic properties of coupling partners. Subjection of electron-rich β-aminoacrylates with electron-deficient halides and alkenes to the optimized conditions leads to the formation of quinolines in good yields after in situ oxidation of tetrahydroquinolines. Detailed mechanistic studies which reveal an unexpected reaction pathway is described. (Figure presented.).
Iridium-catalyzed asymmetric hydrogenation of α-alkylidene succinimides
Liu, Yuanyuan,Zhang, Wanbin
supporting information, p. 2203 - 2206 (2013/03/28)
Not to be out PhOXed! The title reaction provides a new approach to chiral succinimide derivatives with excellent yields and ee values by using a low catalyst loading (0.05 mol %) and mild reaction conditions. Chiral 3-benzyl pyrrolidines and 1-hydroxypyrrolidine-2,5-diones, important structural motifs in natural products and pharmaceuticals, could be readily prepared. BARF -=tetrakis[3,5-bis(trifluoromethyl)phenyl]borate. Copyright
