23282-20-4 Usage
Uses
Used in Agricultural and Environmental Research:
NIVALENOL is used as a subject of study in agricultural and environmental research for understanding its effects on crop health and the potential risks it poses to human and animal health. Researchers investigate methods to detect, prevent, and mitigate the presence of this mycotoxin in the food supply.
Used in Food Safety and Contamination Control:
NIVALENOL is used as a reference point in the development of food safety protocols and contamination control measures. By understanding the properties and risks associated with this mycotoxin, food producers and regulatory agencies can establish guidelines and practices to minimize the presence of NIVALENOL in the food supply and protect public health.
Used in Public Health and Epidemiological Studies:
NIVALENOL is used as a factor in public health and epidemiological studies to assess the prevalence of mycotoxin exposure and its potential impact on human health. This information can help inform public health policies and interventions aimed at reducing the risk of mycotoxin-related illnesses.
Safety Profile
Poison by intravenous,intraperitoneal, and subcutaneous routes. Mutation datareported. A skin irritant. When heated to decomposition itemits acrid smoke and irritating fumes.
Check Digit Verification of cas no
The CAS Registry Mumber 23282-20-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,2,8 and 2 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 23282-20:
(7*2)+(6*3)+(5*2)+(4*8)+(3*2)+(2*2)+(1*0)=84
84 % 10 = 4
So 23282-20-4 is a valid CAS Registry Number.
InChI:InChI=1/C15H20O7/c1-6-3-7-14(4-16,11(20)8(6)17)13(2)10(19)9(18)12(22-7)15(13)5-21-15/h3,7,9-12,16,18-20H,4-5H2,1-2H3/t7-,9-,10-,11-,12-,13-,14-,15+/m1/s1
23282-20-4Relevant academic research and scientific papers
Preparation, Purification, and NMR Spectra of Some Mono- and Dihemisuccinates of the Trichothecene Mycotoxin Nivalenol
Lauren, Denis R.,Smith, Wendy A.,Wilkins, Alistair L.
, p. 828 - 833 (2007/10/02)
4,15-Diacetylnivalenol (DANIV) was produced in liquid culture and purified by fractionation over silica followed by preparative liquid chromatography.Hydrolysis gave nivalenol (NIV), a trichothecene mycotoxin found as a common contaminant in grain grown in the North Island of New Zealand.Reaction of NIV with succinic anhydride in the presence of n-butylboronic acid and (dimethylamino)pyridine produced a mixture of three mono- and two dihemisuccinates.These were separated by semipreparative HPLC.The major product was 3-hemisuccinyl-NIV (3-HS-NIV).Other products were 4-HS-NIV, 15-HS-NIV, 3,4-diHS-NIV, and 3,15-diHS-NIV. 3-HS-NIV was also produced by enzymatic hydrolysis of 3-HS-DANIV.
Phytotoxic Compounds Produced by Fusarium equiseti. Part 7. Reactions and Rearrangement of the 7-Hydroxy-12,13-epoxytrichothec-9-en-8-one Skeleton
Grove, John Frederick
, p. 1731 - 1736 (2007/10/02)
7α,15-Dihydroxy-12,13-epoxytrichothec-9-en-8-ones, e.g. nivalenol and vomitoxin, rearrange under mild basic conditions to the isomeric 7,13-epoxy-A-nortrichothecane-7-carboxylic acid 15-lactones.With hydrogen chloride, normal addition to the 12,13-epoxide of these compounds occurs, with retention of configuration at C-12, and the more usual rearrangement to the 2β-chloroaprotrichothec-9-en-8-one skeleton is not seen.Catalytic hydrogenation of diacetylnivalenol takes place from the β-face to give correspoding (9R)-trichothecan-8-one.Reliable procedures for the preparation of vomotoxin and nivalenol from their acetates are outlined.
