23289-12-5Relevant academic research and scientific papers
Heterocyclization of thiocarbonohydrazides: Facile synthesis of 5-unsubstituted-1,3,4-thiadiazoles
Hassan, Alaa A.,Abdel-Latif, Fathy F.,Aziz, Mohamed Abdel,Mostafa, Sara M.,Br?se, Stefan,Nieger, Martin
, p. 1183 - 1186 (2015/09/01)
2-(Hydrazinecarbothioyl)-N-substituted hydrazinecarbothioamides react with 2,3,5,6-tetrachloro-1,4-benzoquinone in high yields in a novel fast and facile method to give 5-unsubstituted-1,3,4-thiadiazole-2-amine derivatives. The synthesized compounds were characterized by spectroscopic methods and confirmed by using X-ray crystallography. A rationale for the formation of the products is presented.
NEW METHODS AND REAGENTS IN ORGANIC SYNTHESIS. 53. LITHIUM TRIMETHYLSILYLDIAZOMETHANE: A NEW SYNTHON FOR THE PREPARATION OF 2-AMINO-1,3,4-THIADIAZOLES FROM ISOTHIOCYANATES
Aoyama, Toyohiko,Kabeya, Mototsugu,Fukushima, Atsuko,Shioiri, Takayuki
, p. 2367 - 2370 (2007/10/02)
Lithium trimethylsilyldiazomethane reacts smoothly with isothiocyanates in diethyl ether to give 2-amino-1,3,4-thiadiazoles in good yields.
