232918-07-9Relevant academic research and scientific papers
αvβ3 antagonists based on a central benzoic acid scaffold
Will,Breipohl,Gourvest,Ruxer,Doucet,Auberval,Baron,Gaillard,Gadek,Knolle,Stilz,Peyman
, p. 567 - 572 (2007/10/03)
A series of novel, highly potent αvβ3 antagonists based on a benzoic acid scaffold and containing an acylguanidine as an Arg-mimetic and sulfonamide side chains is described. The compounds are selective against the fibrinogen recepto
Sulfonamide derivatives as inhibitors of bone resorption and as inhibitors of cell adhesion
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, (2008/06/13)
Sulfonamide derivatives, their physiologically tolerable salts and their prodrugs according to the present invention are vitronectin receptor antagonists and inhibitors of cell adhesion, as well as inhibit bone resorption by osteoclasts. These derivatives
