23297-31-6

Basic information

• Product Name: β-alaninate
• CAS NO: 23297-31-6
• Molecular Weight: 88.0861
• Mol File: 23297-31-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: β-alaninate(CAS DataBase Reference)
• NIST Chemistry Reference: β-alaninate(23297-31-6)
• EPA Substance Registry System: β-alaninate(23297-31-6)

Safety Data

• Hazardous Substances Data: 23297-31-6(Hazardous Substances Data)

Upstream product

• 69689-45-8 N-benzoyl-β-lactam 
• 873073-31-5 1-(4-nitrobenzoyl)-1-azetidin-2-one 
• 873073-29-1 1-(4-methoxybenzoyl)-1-azetidin-2-one 
• 873073-30-4 1-(4-chlorobenzoyl)-1-azetidin-2-one 

Relevant articles and documents

Competitive endo- and exo-cyclic C-N fission in the hydrolysis of N-aroyl β-lactams

The balance between endo- and exo-cyclic C-N fission in the hydrolysis of N-aroyl β-lactams shows that the difference in reactivity between strained β-lactams and their acyclic analogues is minimal. Attack of hydroxide ion occurs preferentially at the exocyclic acyl centre rather than that of the β-lactam during the hydrolysis of N-p-nitrobenzoyl β-lactam. In general, both endo- and exo-cyclic C-N bond fission occurs in the alkaline hydrolysis of N-aroyl β-lactams, the ratio of which varies with the aryl substituent. Hence, the Bronsted β-values differ for the two processes: -0.55 for the ring-opening reaction and -1.54 for the exocyclic C-N bond fission reaction. For the pH-independent and acid-catalysed hydrolysis of N-benzoyl β-lactam, less than 3% of products are derived from exocyclic C-N bond fission.