23301-01-1Relevant academic research and scientific papers
Synthesis of 2-alkenyl-2H-indazoles from 2-(2-carbonylmethyl)-2H-indazoles
Lin, Mei-Huey,Liang, Kung-Yu,Tsai, Chang-Hsien,Chen, Yu-Chun,Hsiao, Hung-Chang,Li, Yi-Syuan,Chen, Chung-Hao,Wu, Hau-Chun
, (2016)
A procedure has been developed for synthesis of 2-alkenyl-2H-indazoles starting from 2-(2-carbonylmethyl)-2H-indazoles, which are prepared by gallium/aluminium- and aluminium-mediated, direct, regioselective alkylation of indazoles with α-bromocarbonyl compounds. The structure of 3-(2H-indazol-2-yl)-2H-chromen-2-one was proven by X-ray crystallography. The styrene- and coumarin-2H-indazoles produced by using the newmethod were found to have interesting fluorescence properties.
