23314-13-8

Usage

Derived from

Biphenyl (aromatic hydrocarbon)

Contains

An amine group

Common uses

Synthesis of pharmaceuticals, agrochemicals, and materials

Potential applications

Therapeutic and industrial

Biological activities

Anti-inflammatory and anticancer properties

Role in organic chemistry

Building block for the preparation of other organic compounds

Upstream product

• 3245-43-0 1-(2-bromoethoxy)-2-phenylbenzene 
• 607-04-5 biphenyl-2-yl-(2-chloro-ethyl)-ether 
• 90-43-7 2-Phenylphenol 
• 1885-57-0 biphenyl-4-yl-(2-chloro-ethyl)-ether 
• 1074-82-4 potassium phtalimide 

Downstream Products

• 1220748-18-4 C₃₀H₂₉NO₃ 

Relevant academic research and scientific papers

Discovery of a new series of 5-HT1A receptor agonists

Starting from compounds previously identified as α1-adrenoceptor antagonists that were also found to bind to the 5-HT1A receptor, in an attempt to separate the two activities, a new series of 5-HT1A receptor agonists was identified and shown to have high potency and/or high selectivity. Of these, compound 13, which combines high selectivity (5-HT1A/α1 = 151) and good agonist potency (pD2 = 7.82; Emax = 76), was found to be the most interesting.

Substituted alpha-aminosulphonyl-acetohydroxamic acids as therapeutic agents

Compounds of formula (I): where the substituents are as defined herein, and salts thereof, are matrix metalloprotease inhibitors.