23316-76-9Relevant academic research and scientific papers
Stereoselective synthesis of N1-6-methyluridine and related 2-substituted analogues
Radi, Marco,Petricci, Elena,Corelli, Federico,Botta, Maurizio
, p. 79 - 83 (2008/02/13)
Coupling reaction of 2-substituted-6-methyl-4(3H)-pyrimidinones (1a,b) with 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose (ABR) afforded the corresponding N1-2,6-disubstituted nucleosides (2a,b) without any trace of the N3-isomer.
Nucleoside Syntheses, XXII. Nucleoside Synthesis with Trimethylsilyl Triflate and Perchlorate as Catalysts
Vorbrueggen, Helmut,Krolikiewicz, Konrad,Bennua, Baerbel
, p. 1234 - 1255 (2007/10/02)
The novel Lewis acids (CH3)3SiOSO2CF3 (5), (CH3)3SiOSO2C4F9 (6), and (CH3)3SiClO4 (4) are highly selective and efficient Friedel-Crafts catalysts for nucleoside formation from silylated heterocycles and peracylated sugars as well as for rearrangements of persilylated protected nucleosides.With basic silylated heterocycles these new catalysts give much higher yields of the natural N-1-nucleosides than with SnCl4.
