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23325-78-2

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USP/BP standard Cephalexin Monohydrate CAS 23325-78-2 supplied by manufacturer
Cas No: 23325-78-2
USD $ 30.0-80.0 / Kilogram 10 Kilogram 20 Metric Ton/Month Wuhan Fortuna Chemical Co.,Ltd Contact Supplier
Cephalexin monohydrate
Cas No: 23325-78-2
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Dayang Chem (Hangzhou) Co.,Ltd. Contact Supplier
High quality Cephalexin Monohydrate supplier in China
Cas No: 23325-78-2
No Data No Data Metric Ton/Day Simagchem Corporation Contact Supplier
High purity 23325-78-2 Cephalexin monohydrate
Cas No: 23325-78-2
USD $ 100.0-500.0 / Gram 1 Gram 99999 Gram/Year Hangzhou Dingyan Chem Co., Ltd Contact Supplier
Factory Price API 99% CEPHALEXIN MONOHYDRATE 23325-78-2 GMP Manufacturer
Cas No: 23325-78-2
USD $ 0.1-0.1 / Gram 1 Gram 100 Metric Ton/Year Xi'an Xszo Chem Co., Ltd. Contact Supplier
Factory Supply Cephalexin Monohydrate
Cas No: 23325-78-2
No Data 1 1 Ality Chemical Corporation Contact Supplier
CEFALEXIN
Cas No: 23325-78-2
No Data 25 Kilogram Metric Ton/Day HANGZHOU CLAKE BIOTECH CO.,LTD Contact Supplier
cefalexin monohydrat
Cas No: 23325-78-2
No Data 10 Milligram Amadis Chemical Co., Ltd. Contact Supplier
Cephalexin monohydrate
Cas No: 23325-78-2
USD $ 1.0-1.0 / Kilogram 1 Kilogram 1000 Metric Ton/Year Henan Sinotech Import&Export Corporation Contact Supplier
Pharmaceutical Grade CAS 23325-78-2 with competitive price
Cas No: 23325-78-2
USD $ 139.0-210.0 / Kilogram 1 Kilogram 1000 Kilogram/Day Zhuozhou Wenxi import and Export Co., Ltd Contact Supplier

23325-78-2 Usage

Therapeutic Function

Antibiotic

Brand name

Keflex (Panixine (Ranbaxy).

Originator

Ceporex,Glaxo,UK,1970

Chemical Properties

White to Off-White Solid

Uses

Cephalosporin antibacterial.

Uses

A semisynthetic cephalorsporin antibiotic.

Definition

ChEBI: The hydrate of cephalexin.

Manufacturing Process

To a 1 liter flask containing dimethylformamide at 0°C, was added 24.8 g sodium N-(2-methoxycarbonyl-1-methylvinyl)-D-α-phenylglycine (prepared from sodium D-α-phenylglycine and methyl acetoacetate). The mixture was cooled to -40°C and methyl chloroformate (7.5 ml) and dimethylbenzylamine (0.26 ml) added. After stirring for 25 minutes, p-nitrobenzyl 7- aminodesacetoxycephalosporanate (32.8 g) in the form of its hydrochloride salt was added, followed by triethylamine (12.1 ml) and dimethylformamide (140 ml) over a period of 20 minutes. The reaction mixture was stirred for 2 hours at -25°C to -35°C, then warmed to 0°C and water (32 ml) added. To the resultant solution, hydrochloric acid (54 ml) was added followed by zinc (21.8 g) in portions over a period of 5 minutes, the temperature being maintained at 5°C to 10°C. Further hydrochloric acid (35 ml) was added and the solution stirred at 15°C to 20°C for 7 hours. The pH was adjusted to 3.3 with triethylamine and semicarbazidehydrochloride (9.5 g) added. The mixture was brought back to pH 3 with further triethylamine, then stirred for 30 minutes at pH 3. The resultant mixture was adjusted slowly over 4 hours to pH 6.8 by addition of triethylamine, seeding being carried out when pH 4.5 was reached. The precipitated cephalexin was filtered off, washed with dimethylformamide (200 ml) and the cephalexin recovered, yield 75%.

Uses

Semi-synthetic cephalosporin antibiotic.
InChI:InChI=1/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15?/m1/s1

23325-78-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name cephalexin monohydrate

1.2 Other means of identification

Product number -
Other names Cephalexin monohydrate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:23325-78-2 SDS

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