Cas 233272-34-9,(S)-(+)-7-nitro-N-benzyloxycarbonyl-3-methoxycarbonyl-1,2,3,4-tetrahydroisoquinoline

233272-34-9

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Basic information

Product Name: (S)-(+)-7-nitro-N-benzyloxycarbonyl-3-methoxycarbonyl-1,2,3,4-tetrahydroisoquinoline
Synonyms: (S)-(+)-7-nitro-N-benzyloxycarbonyl-3-methoxycarbonyl-1,2,3,4-tetrahydroisoquinoline
CAS NO:233272-34-9
Molecular Formula:
Molecular Weight: 370.362
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: (S)-(+)-7-nitro-N-benzyloxycarbonyl-3-methoxycarbonyl-1,2,3,4-tetrahydroisoquinoline(CAS DataBase Reference)
NIST Chemistry Reference: (S)-(+)-7-nitro-N-benzyloxycarbonyl-3-methoxycarbonyl-1,2,3,4-tetrahydroisoquinoline(233272-34-9)
EPA Substance Registry System: (S)-(+)-7-nitro-N-benzyloxycarbonyl-3-methoxycarbonyl-1,2,3,4-tetrahydroisoquinoline(233272-34-9)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 233272-34-9(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 233272-34-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,3,3,2,7 and 2 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 233272-34:
(8*2)+(7*3)+(6*3)+(5*2)+(4*7)+(3*2)+(2*3)+(1*4)=109
109 % 10 = 9
So 233272-34-9 is a valid CAS Registry Number.

233272-34-9Upstream product

233272-34-9Downstream Products

233272-34-9Relevant academic research and scientific papers

Enantioselective synthesis of constrained phenylalanine analogues

Chaturvedula, Prasad V.,Mercer, Stephen E.,Guernon, Leatte,MacOr, John E.,Dubowchik, Gene M.

scheme or table, p. 5588 - 5591 (2010/10/19)

Constrained phenylalanine derivatives containing hydrophobic groups and hydrogen bond acceptor and/or donor functionalities were synthesized through a tandem palladium-mediated Heck reaction followed by a rhodium(II)-catalyzed asymmetric hydrogenation. Ar

Novel tetrahydroisoquinoline derivatives with inhibitory activities against acyl-CoA: Cholesterol acyltransferase and lipid peroxidation

Ohta, Masaru,Takahashi, Kenji,Kasai, Masayasu,Shoji, Yoshimichi,Kunishiro, Kazuyoshi,Miike, Tomohiro,Kanda, Mamoru,Mukai, Chisato,Shirahase, Hiroaki

experimental part, p. 1066 - 1076 (2010/11/16)

To find a novel acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor with anti-lipid peroxidative activity, a series of tetrahydroisoquinoline derivatives were synthesized and evaluated. A compound with a N-(4-hydroxy-2,3,5-trimethylphenyl)carbamoyl moi

TETRAHYDROISOQUINOLINE COMPOUND AND MEDICINAL USE THEREOF

-

Page/Page column 45, (2010/11/28)

The present invention provide a tetrahydroisoquinoline compound having a superior ACAT-inhibitory activity and/or anti-oxidation action, particularly, novel compound represented by the formula (I) (wherein each symbol is as described in the specification) and a pharmaceutically acceptable salt thereof.

3,7-Disubstituted-1,2,3,4-tetrahydroisoquinolines display remarkable potency and selectivity as inhibitors of phenylethanolamine N- methyltransferase versus the α2-adrenoceptor(1a)

Grunewald, Gary L.,Dahanukar, Vilas H.,Teoh, Bee,Criscione, Kevin R.

, p. 1982 - 1990 (2007/10/03)

3-Hydroxymethyl-1,2,3,4-tetrahydroisoquinoline (4) is a more selective inhibitor (PNMT K(i) = 1.1 μM, α2 K(i) = 6.6 μM, selectivity (α2 K(i)/PNMT K(i)) = 6.0) of phenylethanolamine N-methyltransferase (PNMT, EC 2.1.1.28), with respec

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